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In this paper the stability of the zero equilibrium of a system with time delay is studied. The critical case of a multiple zero root of the characteristic equation of the linearized system is treated by applying a Malkin type theorem and using a complete Lyapunov-Krasovskii functional. An application to a model for malaria under treatment considering the action of the immune system is presented.

In this paper, we study two mathematical models, involving delay differential equations, which describe the processes of erythropoiesis and leukopoiesis in the case of maintenance therapy for acute lymphoblastic leukemia. All types of possible equilibrium points were determined, and their stability was analyzed. For some of the equilibrium points, conditions for parameters that imply stability were obtained. When this was not feasible, due to the complexity of the characteristic equation, we discuss the stability through numerical simulations. An important part of the stability study for each model is the examination of the critical case of a zero root of the characteristic equation. The mathematical results are accompanied by biological interpretations.

In this paper, we use a generalized form for the Jordan totient function in order to extend the Reciprocal power GCDQ matrices and power LCMQ matrices from the standard domain of natural integers to Euclidean domains. Structural theorems and determinantal arguments defined on both arbitrary and factor-closed q-ordered sets are presented over such domains. We illustrate our work in the case of Gaussian integers.