Obstructive sleep apnoea (OSA) is a respiratory sleep disorder characterized by recurrent episodes of obstructive breathing while a person is asleep due to collapse of the upper respiratory tract,despite ongoing breathing efforts. It is a chronic disorder affecting 2-4% of the population with prevalence to middle age men. Predisposing factors mainly include narrowed upper airway, dysfunctional upper airway dilator muscles, and obesity. It isalso accompanied by various morbidities,including excessive daytime sleepiness,increased risk of traffic, and industrial accidents and cardiovascular complications. Obstructive sleep apnoea has also been linked to other medical conditions like Myocardial Infarction, Congestive Heart Failure, Stroke, and Diabetes Mellitus though not definitively. Suggestive treatment modalities include continuous positive airwaypressure(CPAP), oral appliance therapy, bariatric surgery, uvulopalatopharyngoplasty, maxilla-mandibular advancement. However, a multidisciplinary approach is highly recommended for accurate management of the disease.

Lymphomas are a group of malignant diseases affecting the lymphoreticular system. Lymphoma is the second most common neoplasm of the head and neck after squamous cell carcinoma, but the incidence of lymphomas in the oral cavity and orbit is rare. Non-Hodgkin’s lymphoma (NHL) is less predictable than Hodgkin’s but has a greater predilection to extranodal tissues. Non-Hodgkin’s incidence in extranodal sites accounts for about 20% to 30%, but in the oral cavity, its around 0.1% to 5%. The rarity of incidence in the oral cavity and atypical radiographic features diagnosing a lymphoma is quite a challenge for clinicians. Here we describe a case of 31-year-old male patient with high-grade non-Hodgkin’s lymphoma involving oral cavity with metastasis to orbit, skeletal structures, testes, liver, pancreas and nasopharynx, which is quite rare.