No abstract

No abstract

A convenient, green, and efficient protocol for the synthesis of diversely substituted pyrazolo‐pyrido‐pyrimidines has been described by a simple one‐pot four‐component reaction of hydrazine, ethyl acetoacetate, 6‐amino‐1‐methyluracil, and isatin or aldehyde catalyzed by iodine in water. Environmental friendliness, operational simplicity, low cost, high yields, and applicability to a wide range of readily available starting materials are the key features of this methodology. Most importantly, workup of this very clean strategy involves only filtration and simple washing step without any traditional chromatography and recrystallization purifications, thus reducing time, waste, and cost.

A simple and highly efficient strategy has been documented for the rapid and convenient synthesis of pyrimido[4,5-b]quinoline from aldehydes, 2-hydroxynaphthalene1,4dione and 6-aminouracil in the presence of nano ZnO under aqueous admicellar system at 80 °C.

No abstract