Aims: The research aimed to study the response of West Sumatera brown rice growth on nutrient culture media. Study Design:  Factorial design with 2 factors in completely randomized design. Place and Duration of Study: The research was conducted in Laboratory of Tissue Culture, Laboratory of Seed Technology and Shade net house, Faculty of Agriculture, Andalas University, Padang, Indonesia from May to July 2019. Methodology: Factorial design with 2 factors in completely randomized design was used in the research. The first factor was brown rice genotypes (Talang Babungo, Sigambiri, Pido Manggih, Labuh Baru, Balingka, Situjuah, Banuhampu, Pulen Talao, Ladang Talamao and Sikarujuik. The second factor was FeSo2 concentrations (0 ppm, 250 ppm, 500 ppm and 750 ppm). The data was analysed using F test  5% and continued by Duncan’s New Multiple Range Test (DNMRT) 5%. Results: The result showed that there was interaction between brown rice genotypes and Fe concentrations to plant height and root dry weight in early growth stage. According the stress sensitivity index, Sigambiri and Ladang Talamao were the tolerant genotypes to high Fe stress and Talang Babungo and Banuhampu were moderately tolerant genotype in high concentration of Fe stress. Conclusion: High Fe concentration affected the brown rice growth. This result can be a consideration to cultivate brown rice in high iron content land.