Background: Monkeypox is a zoonosis. The disease has a similar appearance to chickenpox caused by the varicella-zoster virus (VZV). On May 9th 2019, there was one laboratory-confirmed case of monkeypox reported in Singapore. A man was also suspected of having monkeypox on June 1st 2019 in Surabaya, Indonesia, a neighboring country. Objective: To report on a suspected case of monkeypox with differential diagnosis to chickenpox. Case: A 51-year-old male was suspected of having monkeypox after a differential diagnosis of chickenpox. His chief complaint was multiple blisters on his body. From the dermatological status on his facial, trunk and extremity regions, there were multiple pleiomorphic vesicles, some with umbilication, with a centripetal distribution, and crusts. Methods and Results: A PCR using VZV specific primers, followed by genome sequencing showed homologies of more than 99 % to other VZVs and less than 50% to Monkeypox sequences. Conclusion: Molecular laboratory techniques have confirmed the case as chickenpox.
Flush, transitory erythema, persistent erythema, telangiectasia, papules, pustules, and stinging or burning discomfort on the facial skin are all symptoms of rosacea, a chronic inflammatory skin disease. Although its exact cause is unknown, rosacea has been linked to the autonomic nervous system, immunological system, and blood vessels. Bacillus oleronius, Demodex folliculorum, Cutibacterium acnes, Staphylococcus epidermidis, and Even the microbes that live in your gut have a role in the emergence of rosacea. The existence of alteration in microbiome of the skin and gut can be a consideration for giving probiotics as adjuvant therapy to maintain the balance of microbiome in rosacea
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