ABSTRAK Kulit buah Mundar (G. forbesii King.) merupakan tanaman endemik yang berasal dari Kalimantan Selatan yang berpotensi memiliki aktivitas antioksidan. Penelitian ini dilakukan untuk menguji aktivitas antioksidan ekstrak etanol 30% dan 70% kulit buah Mundar (G. forbesii King.) yang diperoleh dengan metode ekstraksi sokhletasi. Pengujian aktivitas antioksidan dilakukan dengan metode DPPH (2,2-Diphenyl-1-Picrylhydrazil) secara kualititatif dan kuantitatif dengan kuersetin sebagai kontrol positif. Hasil uji aktivitas antioksidan ekstrak etanol 30% dan 70% kulit buah Mundar (G. forbesii King.) secara kualitatif menunjukkan adanya aktivitas antioksidan yang ditandai dengan noda kuning pada plat kromatografi lapis tipis (KLT) setelah disemprot dengan larutan DPPH 0,1mM. Hasil uji aktivitas antioksidan secara kuantitatif menghasilkan nilai IC50 (Inhibitory Concentration) secara berturut-turut dari ekstrak etanol 30% kulit buah Mundar (G. forbesii King.); ekstrak etanol 70% kulit buah Mundar (G. forbesii King.); dan kuersetin adalah 717,01 ppm; 534,69 ppm; dan 2,04 ppm. Ekstrak etanol 70% kulit buah Mundar (G. forbesii King.) memiliki aktivitas antioksidan yang lebih baik dibandingkan ekstrak etanol 30% kulit buah Mundar (G. forbesii King.). Kata kunci: Kulit buah Mundar (G. forbesii King.), antioksidan, DPPH, kromatografi lapis tipis (KLT), IC50 ABSTRACT Antioxidants are compounds that can counteract free radicals. Mundar rind (Garcinia forbesii King.) is endemic plants from South Kalimantan that has the potential antioxidant activity. This research was conducted antioxidant activity test of ethanolic extract 30% and 70% of Mundar rind (G. forbesii King.) obtained by soxhlet extraction method. Antioxidant activity test of Mundar rind (G. forbesii King.) used the DPPH (2,2-Diphenyl-1-Picrylhydrazil) method qualitatively and quantitatively with quercetin as a positive control. The results of the antioxidant activity test qualitatively of ethanolic extract 30% and 70% of Mundar rind (G. forbesii King.) showed antioxidant activity marked with a yellow spot with purple background on kromatogram after sprayed with DPPH solution 0,1mM. The results of the antioxidant activity test quantitatively obtained IC50(Inhibitory Concentration) value respectively of ethanolic extract 30%; ethanolic extract 70%; and quercetin were 717,01 ppm; 534,69 ppm; and 2,04 ppm. The ethanolic extract 70% of Mundar rind (G. forbesii King.) had better antioxidant activity than the ethanolic extract 30% of Mundar rind (G. forbesii King.) Keywords: Mundar rind (G. Forbesii King.), antioxidant, DPPH, thin layer chromatography (TLC), IC50
Background: Dayak Onion (Eleutherine bulbosa Urb.) is a typical plant of Kalimantan which is traditionally used by the Dayak community as a medicinal plant. Dayak onion bulbs have been proven had many pharmacology activities. Objective: This study aims to determine the nonspesific and specific parameters of 70% ethanol extract of Eleutherine bulbosa Urb. Total flavonoids was also quantified Methods:. Eleutherine bulbosa Urb was extracted with maseration method used etanol 70 % as solvent. Determination of non-spesific includes by determined specific gravity, water content, total ash content, acid insoluble ash content, residual sovents, heavy metanol contamination, microbial contamination, mold and yeast contamination. Determination of specific parameters included extract identity, organoleptic extract, water/ethanol soluble content, chromatography profile. Total flavonoid content were quantified with colorimetric method. Results: there were no significance difference between nonspesific and specific parameters Eleutherine bulbosa Urb from three different locations. Measurement of total phenol content and total flavonoid content respectively form South Borneo were ; 6,499 ± 0,5248 mg QE/g extract, from central borneo were 7,585 ± 0,0437 mgQE/g extract, and from east borneo were 5,035 mg ± 0,3887 mgQE/g extract. Conclusion: it can be concluded that bulbs of Eleutherine bulbosa Urb from three locations have characters to similar between each other and bulbs of Eleutherine bulbosa Urb form central borneo had the highest total flavonoid content.
ABSTRAK Perkembangan pengetahuan banyak mengangkat penggunaan bahan alam untuk alternatif pilihan sebagai imunomodulator. Penelitian ini dilakukan untuk mengetahui efek imunomodulator dari infusa umbi Bawang Dayak (Eleutherina palmifolia L. Merr) dengan metode bersihan karbon pada mencit putih jantan. Skrining fitokimia yang diujikan pada umbi Bawang Dayak yaitu uji flavonoid, alkaloid, steroid, kuinon, tanin dan saponin. 25 mencit galur Balb/C dibagi menjadi 5 kelompok yang terdiri dari kelompok P1 sebagai kontrol positif yang diberikan stimuno dosis 0,78 mg/20 gram BB; kelompok P2 yang diberikan aquadest, kelompok P3, P4 dan P5 yang diberikan Infusa umbi Bawang Dayak dengan dosis berturut-turut yaitu 13 mg/20 gBB, 26 mg/20 gBB, dan 52 mg/20 gBB. Perlakuan pemberian diberikan secara oral selama 7 hari. Pada hari ke-8 dilakukan uji imunomodulator dengan metode bersihan karbon. Hasil skrining fitokimia menunjukkan adanya senyawa saponin, flavonoid dan alkaloid. Hasil Uji imunomodulator menunjukkan adanya infusa umbi Bawang Dayak dosis 52 mg/20 gBB menunjukkan efek imunomodulator terbesar. Infusa umbi Bawang Dayak memiliki aktivitas imunmodulator. Kata Kunci : Imunomodulator, Infusa, Umbi Bawang Dayak, Eleutherina palmifolia ABSTRACT The development of knowledge raised the use of natural materials as an alternative choice as an immunomodulator. The aim of this study was to know the imunomodulatory effect of Bawang Dayak Bulb (Eleutherina palmifolia L. Merr) by using carbon clearance method on male mice. The phytochemical screening were tested to flavonoids, alkaloids, steroids, quinones, tanins, and saponins. 25 male Balb/C mice divided into 5 groups consisting of P1 groups as positive control given stimuno 0,78 mg/20 gBB; P2 groups as negative control given aquadest, P3, P4 and P5 groups given Bawang Dayak Bulb Infusion with doses respectively 13 mg/20 gBB, 26 mg/20 gBB, and 52 mg/20 gBB. Each groups were adminstered orally one a day for seven days. On the eighth day, imunomodulatory test were performed by using carbon clearence method. The phytochemical screening revealed the presence of flavonoids, alkaloids, and saponins. Results of imunommodulatory test showed Bawang Dayak Bulb infusion doses 52 mg/20 gBB has the highest immunomodulatory effect. Bawang Dayak Bulb Infusion showed imunomodulatory effect. Keywords : Imunomodulator, Infusion, Bawang Dayak Bulb, Eleutherina Palmifolia
Introduction: Eleutherine bulbosa Urb is a plant species with medicinal properties, including anti-inflammatory, widely relied upon in traditional practices. For this reason, the present research was intended to assess and, thus, ensure the safety of this plant for conventional medicinal purposes using a toxicity test study. Methods: The acute toxicity test of the ethanolic extract of E. bulbosa Urb (EEEB) used the method adopted from the Organization Economic Cooperation and Development (OECD) guidelines 425 for testing Wistar rats. Results: During 14 days of the acute toxicity study, there were no significant changes in rat weight, no mortality, and no signs of toxicity after the oral EEEB administration at 2000 mg/kg body weight (bw). The limit test showed that the LD50 of EEEB was higher than 2000 mg/kg bw. Conclusion: EEEB has low toxicity because its LD50 is higher than the limit test results.
ABSTRAKKelompok Wani Tani (KWT) Sri Rejeki di Kelurahan Landasan Ulin, Kecamatan Lianganggang, merupakan salah satu kelompok wanita yang membudidayakan sayuran dan tanaman yang bisa dimanfaatkan sebagai tanaman obat, diantaranya bunga telang (Clitoria ternatea). Bunga telang yang dihasilkan biasanya dijual dalam bentuk segar yang masih memiliki keterbatasan dalam penyimpanan, yaitu akan cepat layu dan ditumbuhi jamur. Tujuan kegiatan ini adalah melakukan edukasi khasiat tanaman, pelatihan pembuatan simplisia dan pengembangan produk olahan berupa celupan dari bunga telang untuk dapat meningkatkan nilai jual hasil panen. Metode kegiatan adalah sosialisasi, penyuluhan, pelatihan dan pembuatan simplisia dan celupan. Berdasarkan hasil pengukuran kuesioner, diketahui bahwa sebelum edukasi, 58.82 % petani memiliki tingkat pengetahuan yang baik tentang khasiat bunga telang, sedangkan 41.18% mengetahui tingkat pengetahuan cukup. Setelah diberikan edukasi tentang khasiat tanaman bunga telang, terjadi peningkatan tingkat pengetahuan, yaitu 94.12% menjadi baik. Untuk pelatihan pembuatan simplisia dan celupan, hasil dari kuesioner 35.29 % petani telah memiliki keterampilan yang baik tentang pengolahan simplisia dan celupan bunga telang, sedangkan 64.71% memiliki keterampilan cukup. Setelah diberikan pelatihan, terjadi peningkatan keterampilan anggota, yaitu 94.12% menjadi baik. Dapat disimpulkan bahwa terjadi peningkatan pengetahuan petani tentang khasiat bunga telang, serta petani memiliki keterampilan yang baik dalam mengolah bunga telang segar menjadi simplisia dan celupan. Kata kunci : pemberdayaan; bunga telang; simplisia; tingkat pengetahuan; keterampilan ABSTRACTThe Sri Rejeki Women Farming Group (SRWFG) in Banjarbaru is one of the women's groups who cultivate vegetables and plants which can also be used as medicinal plants, including the butterfly pea flower (Clitoria ternatea). Butterfly pea flower are usually sold in fresh form. Butterfly pea flowers in fresh will quickly wither or overgrown with microorganisms such as fungi. The SRWFG also not knowing the benefits of the plant for health. The purpose of this activity was to educated the efficacy of plants, trained in making simplicia and dipping of butterfly pea flower to increase the selling value. The method of activity was socialization, counseling, training and making simplicia and dipping. Based on the results of the questionnaire measurements, it was known that before education, 58.82% of farmers had a good level of knowledge about the efficacy of the telang flower, while 41.18% knew the level of knowledge was sufficient. After being given education about the efficacy of the butterfly pea flower plant, there was an increase in the level of knowledge of farmers, which was 94.12% to good. For training in making simplicia and dyes, it was found that previously, 35.29% of farmers had good skills in processing simplicia and dyed butterfly pea flower, while 64.71% had sufficient skills. After being given training, there was an increase in the skills of members, namely 94.12% to be good. It can be concluded that there was an increase in farmers' knowledge about the efficacy of butterfly pea flowers, and farmers have good skills in processing fresh butterfly pea flowers into simplicia and dyes. Keywords : empowerment; butterfly pea flower; simplicia; knowledge; skill
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