Background/Aims: The aim of this study was to compare the utility of the revised Mayo risk model (rMRM) and Child-Pugh scores (CPSs) for predicting the prognosis of disease in patients with primary sclerosing cholangitis (PSC). Materials and Methods: Patients were divided into 2 groups: Group I (37 patients; alive and not requiring liver transplantation) and Group II (8 patients; deceased or requiring liver transplantation). rMRM suggests the possible survival percentage over a 4-year period. Thus, rMRM scores and CPSs on the first visit were calculated from the data at the time of diagnosis for patients diagnosed with PSC <4 years ago. rMRM scores and CPSs of patients with >4 years of follow-up were calculated using data from the visit 4 years prior to their last follow-up. Results: Bivariate analyses showed that need for liver transplantation/mortality was correlated with either first visit CPS (r=0.481, p=0.001) or rMRM (r=0.452, p=0.002). Analysis of the area under the curve showed that both models performed similarly in terms of predicting the need for liver transplantation/mortality (rMRM: 0.780; CPS: 0.762; p=0.8). There was a significant difference in Kaplan-Meier survival rates between Group I and Group II for both risk models (rMRM: p<0.001; CPS: p<0.001) when the decisive event was death or need for liver transplantation. Conclusion: Both rMRM and CPSs are useful in risk assessment of patients with PSC. The ability to predict prognosis is similar for both risk models.
Piyojenik karaci¤er abseleri s›kl›kla biliyer sistem patolojileri sonucu geliflmekte olup, hastadan hastaya de¤iflmekle birlikte tedavide en s›k antibiyotik tedavisi ve perkütan drenaj uygulanmaktad›r. Bunlara ilave olarak ancak cerrahi giriflim ile tedavi edilebilen durumlar da söz konusudur. Son dönemde özellikle biliyer sistem patolojileri sonucu geliflen abselerin sfinkterotomi, darl›k dilatasyonlar›, stent yerlefltirilmesi ve daha da nadir olarak abse pofluna nazobiliyer dren yerlefltirilmesi ile endoskopik tedavileri gündeme gelmifltir. Burada asendan kolanjit sonucu pyojenik abse geliflen 3 olgunun abse pofluna nazobiliyer dren yerlefltirilmesi ve sonras› seyirleri ile ilgili verileri sun-may› amaçlad›k. Anahtar kelimeler: Karaci¤er absesi, endoskopik retrograde kolanjiyografi, drenaj Pyogenic liver abscess generally occurs secondary to biliary system pathologies, and first-line treatment consists of antibiotherapy together with percutaneous drainage, although it can vary patient to patient. In addition, in some cases, surgical management may be necessary. Recently, endoscopic treatment of liver abscesses, especially those secondary to biliary system pathologies, via sphincterotomy, dilatation of strictures, stent replacement, and nasobiliary drain replacement to the abscess pouch, has became a current issue of interest. In this case series, we aimed to present the clinical course of three patients with pyogenic liver abscess secondary to ascending cholangitis who were managed by nasobiliary drain replacement to the abscess pouch.
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