This article reports a multilayer implantable biosensor for a continuous glucose monitoring system, tested on rats to determine the relationship between intravenous glucose level and resonance frequency of implant antenna sensor. An implantable antenna sensor with the volume 330.9 mm 3 is tested in three rats as an animal model. This antenna biosensor operates in the Medical Implant Communication Service frequency band (402-405 MHz) with the simulated and measured maximum gains of −13.33 and −21.1 dB, respectively. The specific absorption rate obtained is within the standard limits. An oral glucose tolerance test is proposed to obtain the variation in blood glucose level in the animal's body during measurement. The resonance frequency shift and the corresponding blood glucose level are observed at a regular interval of 30 minutes. A frequency shift of 4.94 kHz per mg/dL is observed. Also, the results related to the reflection coefficient and the factors affecting sensor performance are discussed. The biosensor performance is validated using the proposed simple linear regression model.

Abstract. The emerging techniques in the sensor field include an antenna as a bio-sensor. A simple Planar Inverted F antenna (PIFA) as an implantable glucose sensor to detect variation in glucose level is presented in this paper. The work includes design of PIF antenna using HFSS software and in vitro testing as a sensor with various glucose level in synthetic blood. The antenna is designed to resonate at frequency 530 MHz for demonstration purpose. The shift in the resonant frequency of 3.54 kHz per 1 mg/dl is observed with respect to change in glucose level concentration.

No abstract

No abstract

No abstract