Background: A Corona virus pandemic now has had a huge impact on quality of life all around the world. People's mental health has been affected by quarantine. The economic delays could have long term impacts on the psychology of students as they are more likely to be graduated later than they have expected. The number of factors contributed to gravitate the psychological disturbances including online education, financial worries and academic pressure. Aims and Objectives: This Study was to determine the level of Depression, Anxiety and Stress among Students during COVID-19 Pandemic. Furthermore, to see if there's a correlation between demographic profile and the DASS-21. Materials and methods: A cross-sectional survey was conducted among the healthcare students using DASS-21 which included a conventional DASS questionnaire along with demographic characteristics. A Google form link was shared through social media-WhatsApp and E-mail and data was collected and analyzed using excel sheet to examine the levels of depression, anxiety, and stress among students. Results: The study enrolled a total of 303 students. The prevalence of moderate depression, anxiety, and stress was found to be 37.9%, 337.9%, 34.9% and 33%, respectively. Males were represented up to 54.13 percent of the population, while females accounted for 45.87 percent. Female responders were more likely than their male counterparts to experience depression and anxiety, whereas stress levels were found to be comparable in both genders. Conclusion: The average scores of depression, anxiety, and stress in this study were significantly high. Depression, anxiety, and stress are now all associated with a variety of causes. Students develop depression and anxiety as a result of a lack of academic and social life. Students may be stressed due to a lack of exercise and economic difficulties. Keywords: Depression, DASS-21, Mental Health, Pandemic, Students, Social Life