The aim of the present study is to design a mucoadhesive nano-carrier system which retains at the site of application and maximizes the therapeutic potential of anticancer drug as well as reduces their systemic side effects. In the present study PVA nanofibers of Docetaxel were prepared using electrospinning machine. The resulting nanofibers were characterized through various parameters such as surface morphology, drug loading, in-vitro drug release, tensile strength, mucoadhesiveness, drug permeability, degree of swelling and anticancer activities against selective cell lines to establish their therapeutics potential. On the basis of various evaluation results, we may conclude that the current approach comprising polymeric nanofibers can be successfully used for local delivery of anticancer drug.

No abstract

The present chapter covers the designing, development, properties and applications of carbon nanotube-loaded polymer composites. The first section will provide a brief overview of carbon nanotubes (CNTs), their synthesis, properties and functionalization routes. The second section will shed light on the CNT/polymer composites, their types, synthesis routes and characterization. The last section will illustrate the various applications of CNT/polymer composites; important properties, parameters and performance indices backed by comprehensive literature account of the same. The chapter concludes with the current challenges and future aspects.

No abstract

No abstract