Introduction: Coronavirus disease-19 (COVID-19) is a novel infection that sets off a pandemic in a short period. Research has been going on to develop safe and effective vaccines and around 150 are in the process of development. In India, two vaccines have been given emergency approval. There has been a rise in hesitancy toward vaccination not only in India but also worldwide. Materials and Methodology: The study included 697 participants who were not vaccinated. The study questionnaire was administered through online Google Forms and included informed consent, sociodemographic details, questions related to COVID-19 infection and vaccine, and vaccine attitude examination (VAX) scale. Results: Among the 697 participants, 216 (31%) were not willing to get vaccinated. Those with prevailing mental (P = 0.011) or physical health (P < 0.001) problems were of negative opinion toward vaccination because of unforeseen complications. Participants with lower education (P = 0.041), skilled to semi-skilled job (P = 0.028), and joint family (P = 0.006) opined that vaccination was more of commercial profiteering for manufacturing companies. Participants who were married (P = 0.010) and living in a joint family (P = 0.009) setting were more inclined toward a preference for natural immunity. Conclusion: The study highlights that 69% of participants were willing to take the COVID-19 vaccine. Various measures can be taken by different stakeholders to improve the positive attitude. As medical professions, we can improve the positive attitude by actively taking the vaccine and educating the local people about the benefits.

Background: Antidepressant drugs are frequently associated with sexual dysfunction. Sexual side effects affect the patients' quality of life and in the long term and can lead to noncompliance and relapse. However, studies covering many antidepressants with different mechanisms of action are scarce. Aims: The aim of this study is to compare the rates of sexual dysfunction among patients taking escitalopram, desvenlafaxine, and mirtazapine. Settings and Design: Cross-sectional study. Materials and Methods: Arizona Sexual Experience Scale (ASEX), Hamilton Rating Scale for Depression (21 items), and State and Trait Anxiety Inventory. Statistical Analysis Used: Fisher's exact t-test, Chi-square test, and analysis of variance depending on the type of variable. Results: Eighty-four participants (42 males and 42 females) completed all instruments. Of these, 28 were taking escitalopram (13.93 ± 5.15), 28 were taking desvenlafaxine (76.79 ± 25.39), and 28 were taking mirtazapine (16.88 ± 3.88). A substantial number of patients (40.5%, n = 34) had sexual dysfunction. The prevalence of sexual dysfunction varied across the drugs; escitalopram (60.7%), desvenlafaxine (35.7%), and mirtazapine (25%). Regression analysis revealed that the significant factor for sexual dysfunction was the type of antidepressant used. The mirtazapine group's total ASEX score was significantly lower than the scores for escitalopram and desvenlafaxine (χ2 = 7.807, P = 0.020). Conclusion: The incidence of sexual dysfunction is substantially high during antidepressant treatment. The rates of sexual dysfunction differed among antidepressants having different mechanisms of action. Mirtazapine-induced lesser sexual dysfunction compared to desvenlafaxine and escitalopram.

Background: The effects of digital screen use on the physical and mental health of a child are a debated area of research. Studies have established few harmful effects, but the usage among children remains to be high. There is less understanding of the pattern of the digital screen and application usage and its impact on physical and mental health in our population. Aims: To study the pattern of digital screen use among children (5-15 years) and its impact on their physical and mental health. Setting and design: Cross-sectional study conducted in a tertiary care hospital. Materials and Methods: Sociodemographic details of parents and their children, screen time-related questions, pediatric symptom checklist (PSC) for screening of mental health issues, and questions regarding physical health issues in children due to screen use. Statistical Analysis: Data was analyzed using R language. Results: There is a significant association between parents’ education, gender, and the number of children with screen time. YouTube followed by WhatsApp are the commonly used digital applications and smartphones followed by Smart TVs are the commonly used digital gadgets. The physical issues are less than the clinical cut-off values but significantly associated with screen time. Sleep disturbance and avoiding outdoor activity are frequently reported due to screen use. Conclusion: The study highlights the common usage pattern of various digital gadgets and applications among children and their parents; also the demographic factors of parents relating to increased screen time in children. There are no significant clinical mental health issues reported by parents, but a significant association is found between digital screen use with physical and mental health issues.

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Background: Medical postgraduates are exposed to more time in patient care and thereby higher stress. Personality is one of the important factors associated with stress. Studies exist in profiling personality traits and also assessing stress in medical professionals. However, in India, to the best of our knowledge, there are only few studies linking personality traits with stress in different branches of medicine. Aim : The aim of the study was to study the association between big five personality traits and stress among medical postgraduates. Setting and Design This was a cross-sectional study in medical college. Materials and MethodsBig five inventory, perceived stress scale 14. Statistical Analysis Used Chi-square, t-test, analysis of variance, correlation. Results Personality pattern among postgraduates were low on openness (P = 0.000), neuroticism (P = 0.001), and high agreeableness (P = 0.007) compared to general population. Among the different branches pre-paraclinical branches have low openness (P = 0.004), medical branches have high agreeableness (P = 0.000), low openness (P = 0.000), surgical branches have low openness (P = 0.004), and neuroticism (P = 0.003). Married students have high neuroticism (P = 0.007). Perceived stress is high in all variables compared to general population. Among different subjects of medical sciences, it is significantly high in pre-paraclinical (P = 0.001) and clinical branches (P = 0.001). Negative correlation exists between conscientiousness (r = ?0.233, P = 0.025), extraversion (r = ?0.204, P = 0.050), and positive correlation between neuroticism (r = +0.607, P = 0.000) with perceived stress. Conclusions:Medical postgraduates have low openness, neuroticism, and high agreeableness. Perceived stress is high in medical postgraduates in all demographic variables compared to the general population.