Patient safety is important in patient care, especially in primary health care as the first health care providers. The implementation of patient safety at Indonesian's primary health care still varies because there is no specific assessment model. There has been no official report on the incidence of patient safety, but from the primary health care accreditation report, the highest incidence was found in Payakumbuh primary health care, so that the implementation of patient safety at Ibuh primary health care and the factors that influenced must be examined. The study was conducted in December 2017 with a cross section design. Samples were taken with total sampling as much 51 repondents at ibuh primary health care. The data was taken using a valid and reliable questionnaire about patient safety and the factors that influence it. Data were analyzed using chi square test with 95% confidence degree. It was found that 47.1% of respondents have carried out poor patient safety, 47.1% have bad leadership, 45.1% have bad policy, 45.1% bad incident detection, 41.2% have poor mitigation, 45.1 % have dissatisfied patients, 47.1% poor commitment of patients, 49% excessive staff workload, 47.1% lack of staff commitment, 49% bad risk grading, 49% RCA and FMEA not done, and 49% internal audit not good. All variables are significantly related to patient safety. It is recommended that primary health care more improve patient safety by improving leadership, policy, incident detection and mitigation. Giving appreciation for motivating staff and using social media to increases patient satisfaction and commitment.