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The validation is fundamental segment that supports to a commitment of company towards quality assurance. It also assures that product meets its predetermined quality specification and quality. Validation of each steps of manufacturing during multivitamin tablet formulation is called process validation of multivitamin tablets. During past film coating is not much favorable but now for multivitamin tablets film coating is used. The objective is to present a review and to discuss aspects of validation of film coated multivitamin tablets in terms of unit operations; that is, those individual technical operations that comprise the various steps involved in product design and evaluation