Abstract:We communicate this simple but informative report which describes an isolation of a rare variant of Salmonella paratyphi A from a known case of SLE in urine causing clinical and microbiological confusion in diagnosis. Urinary isolation of Salmonella often is unanticipated and a high index of suspicion is required for adequate therapy. Awareness of association between Salmonella spp. and SLE and the timely use of reference laboratories in India is highlighted.