The liver plays several complex but essential roles in the metabolism of amino acids, carbohydrates, and lipids as well as synthesis of proteins. The basic pathophysiology of parenchymal hepatic diseases usually represents a failure in one of these metabolic pathways. 1 Diagnosis of liver pathology rests on physical examination, laboratory investigation, newer imaging techniques, radio isotope scanning. 2 etc. Radiological techniques like ultrasonography and CT scan have roles in evaluation of these liver diseases. Ultrasound plays an important role in evaluation of liver pathology. It helps by detecting lesions, gives clue about its internal structure giving idea about its exact extent: it also gives opportunity to evaluate other abdominal organs. Correlation of ultrasonographic findings with clinical data, laboratory investigations and other radiological investigations lead to make a definite and accurate diagnosis. Thus appropriate management of patients can be done. Present study includes focal and pathology. In present years ultrasonography is widely accepted as first line radiological investigation for liver pathology detection. It is noninvasive cheap, quick free of radiation hazards, comfortable for patients. 3 easy to re-perform and very accurate in hands of skilled operator. With Colour Doppler it is possible to evaluate vascularity of lesion. Ultrasonographic contrast media helps in determination of exact extent of lesion and vascularity of lesion. CT scan is very helpful to evaluate focal as well as diffuse liver pathology. 4 Other investigations like MRI, radionuclide scanning, DSA. 5 etc. are also helpful in liver pathology.

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