Background: Lungs are a major organ involved in infectious, inflammatory, occupational and neoplastic diseases. Lungs are also involved secondarily in almost all terminal events. Autopsy is an important tool to identify cause and manner of death and hence to establish preventive methods. Aims: To study the histopathological pattern of lungs in 100 post mortem cases. Methods: This was an observational study on 100 post-mortem specimens of lungs received in the department of Pathology, GMC, Patiala for a period of 1 year from August 2014 onwards. A thorough gross examination was done on the received lung specimens and sections were taken from the representative areas. These sections were processed for paraffin blocks; slides were prepared and stained with routine Hematoxylin and Eosin stains. The slides were studied under the microscope and the results were noted. Results: Out of the 100 cases, 63 showed terminal nonspecific changes; 19 cases showed the evidence of chronic venous congestion. 10 cases were of pneumonia, 6 of granulomatous pathology, and 1 case of metastatic deposits of adenocarcinoma. Conclusion: Infections are the most commonly noticed primary lung pathology mainly comprising of pneumonia followed by tuberculosis. Hence, efforts should be made for the prevention of these infectious diseases.
Background: Leiomyomas are benign tumors of smooth muscle cells commonly encountered in women of reproductive age group. Aim of this study was to conduct a histopathological study of leiomyomas in hysterectomy specimens and to correlate them with clinical findings.Methods: A prospective study was done on 130 hysterectomy specimens clinically diagnosed as leiomyoma. The specimens were subjected to histopathological examination.Results: In this study, the most common age group was 31-50 years (87.69%). Most common complaint was menorrhagia (51.54%). In endometrium, the most common histopathological diagnosis was proliferative phase (46.15%) followed by endometrial hyperplasia (19.23%). The most common secondary change was hyalinization and the most common site was intramural (62.9%).Conclusions: Hysterectomy is a commonly performed procedure in the management of uterine leiomyomas. The ultimate diagnosis and prognosis depends on the histopathological examination; therefore, every operated specimen must be subjected to histopathology.
Background: Women worldwide suffer from various gynaecological disorders that require hysterectomy as a treatment option. Objectives: Our aim was to conduct a histopathological study of various uterine lesions in hysterectomy specimens and to correlate the findings with clinical indications. Methods: A prospective study was done on 200 hysterectomy specimens. The specimens were fixed in formalin and the tissue was adequately processed. The sections were stained with routine Haematoxylin and Eosin stain. Results: In this study the most common clinical indication for hysterectomy was leiomyoma (57.0%) followed by utero-vaginal prolapse (28.5%). Clinical indication of leiomyoma was confirmed by histopathology in 96.5% cases, whereas that of cervical dysplasia, cervical polyp, squamous cell carcinoma cervix, chronic pelvic inflammatory disease, adenomyosis and endometrial carcinoma was confirmed in 100% cases. Conclusion: The ultimate diagnosis and prognosis depends on the histopathological examination; therefore every operated specimen must be subjected to histopathology.
A cow was reported with the difficulty in parturition since last 12 to 15 hours. Investigation of the birth canal revealed that the cause of dystocia was obstruction, due to large lump at or near the internal os. After relieving the dystocia, it was found that the lump, may be a neoplastic mass, was confirmed as leiomyoma after histopathology.
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