2-Carboxy-6-methoxybenzofuran-3-acetic acid anhydride is utilised for the synthesis of novel polycyclic heteroaromatic compounds in which the benzofuran ring is fused or bound to pyrido [1,4]benzothiazine, thiazole, pyridine, pyrazolopyridine, pyrazole, pyrano-pyridine, and pyrazolo [1,5-a]pyrido[3,2-e]pyrimidines using versatile reaction strategies.

General R 0010Novel Heterocyclic Compounds from 2-Carboxy-6-methoxybenzofuran-3-acetic Acid Anhydride. -Simple and convenient synthetic routes to novel heterocyclic compounds containing pyridobenzothiazine, aminothiazole, pyrazole, and isocoumarin systems start from benzofuran anhydride (I). -(PATANKAR*, J. A.; KHOMBARE, R. T.; KHANWELKAR, R. R.; SHET, J. B.; J. Chem. Res. 2008, 3, 129-133; Dep. Chem., Inst. Sci., Mumbai 400 032, India; Eng.) -H. Toeppel 35-094