Pathogenesis of dengue involves suppression of immune system leading to development of characteristic presentation of haematological picture of thrombocytopenia and leucopenia. Sometimes, this suppression in immune response is responsible for deterioration in clinical status of the patient in spite of all specific and supportive therapy. Certain drugs like steroids are used for rescue therapy in conditions like sepsis. We present a novel use of filgrastim as a rescue therapy in a patient with dengue hemorrhagic fever (DHF) with acute respiratory distress syndrome (ARDS), myocarditis, and febrile neutropenia and not responding to standard management.

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Rasashastra is the backbone of Ayurvedic medicine. Many herbal, mineral and metal Dravya are used in Rasashastra to prepare medicines. Many of these Dravya have inherent poisonous properties also. So it is essential to purify them before converting into medicinal form. But when we go through our classical texts, we find that there are many types of Shodhan methods which were explained with different types of Shodhan Dravya. Shodhan can be done with below said methods -Swedan, Mardan, Nirvapan, Prakshalan, Bhavana, Aatap suska processes etc. Rasatarangini has its own importance in a way that it is the last book of modern Rasashastriya literatures. It has included many ancient as well as modern methods of Yog praparations which are purely practical based. A try has been given to illustrate the importance and methods of purification process explained in Rasatarangini with special emphasis on Maharas Vargiya Dravya.