The R-tree, one of the most popular access methods for rectangles, IS based on the heurlstlc optlmlzatlon of the area of the enclosmg rectangle m each mner node By running numerous experiments m a standardized testbed under highly varying data, queries and operations, we were able to design the R*-tree which mcorporates a combined optlmlzatlon of area, margin and overlap of each enclosmg rectangle m the directory Using our standardized testbed m an exhaustive performance comparison, It turned out that the R*-tree clearly outperforms the exlstmg R-tree varmnts Guttman's linear and quadratic R-tree and Greene's variant of the R-tree This superlorlty of the R*-tree holds for different types of queries and operations, such as map overlay. for both rectangles and multldlmenslonal points m all experiments From a practical pomt of view the R*-tree 1s very attractive because of the followmg two reasons 1 It effrclently supports pomt and spattal data at the same time and 2 Its lmplementatlon cost 1s only slightly higher than that of other R-trees l.Introduction In this paper we will consider spatial access methods (SAMs) which are based on the approxlmatlon of a complex spatial object by the mmlmum boundmg rectangle with the sides of the rectangle parallel to the axes of the data space yIp---+ This work was supported by grant no Kr 670/4-3 from the Deutsche Forschun&iememschaft (German Research Society) and by the Mmlstry of Environmental and Urban Planning of Bremen Pemxss~on to copy wthout fee all or part of this maternal IS granted prowded that the copses are not made or dlstnbuted for dwzct commeraal advantage, the ACM copy&t notice and the title of the pubbcatlon and its date appear, and notw IS gwn that cqymg II by pemuwon of the Assoaatlon for Computmg Machmq To copy othemw, or to repubbsh requ,res a fee and/or speoflc pemllsslon 0 1990 ACM 089791365 5/!90/0@35/0322 $150The most important property of this simple approxlmatlon 1s that a complex object 1s represented by a limited number of bytes Although a lot of mformatlon 1s lost, mnumum bounding rectangles of spatial oblects preserve the most essential geometric properties of the object, 1 e the location of the oblect and the extension of the object in each axisIn [SK 881 we showed that known SAMs organlzmg (mmlmum bounding) rectangles are based on an underlymg point access method (PAM) using one of the followmg three techniques cllpplng, transformation and overlapping regionsThe most popular SAM for storing rectangles 1s the Rtree [Gut 841 Followmg our classlflcatlon, the R-tree 1s based on the PAM B+-tree [Knu 731 usmg the technique over-lapping regions Thus the R-tree can be easily implemented which considerably contributes to Its popularity The R-tree 1s based on a heurlstlc optlmlzatlon The optlmlzatton crlterlon which It persues, 1s to mmlmlze the area of each enclosing rectangle m the mner nodes This crlterlon IS taken for granted and not shown to be the best possible Questions arise such as Why not mnumlze the margin or the overlap of such mlnlmum...
The nuclear genes (acp-1, ACP1) encoding the mitochondrial acyl carrier protein were disrupted in Neurospora crassa and Saccharomyces cerevisiae. In n. crassa acp-1 is a peripheral subunit of the respiratory NADH : ubiquinone oxidoreductase (complex I). S. cerevisiae lacks complex I and its ACP1 appears to be located in the mitochondrial matrix. The loss of acp-1 in N. crassa causes two biochemical lesions. Firstly, the peripheral part of complex I is not assembled, and the membrane part is not properly assembled. The respiratory ubiquinol : cytochrome c oxidoreductase (complex III) and cytochrome c oxidase (complex IV) are made in normal amounts. Secondly, the lysophospholipid content of mitochondrial membranes is increased four-fold. In S. cerevisiae, the loss of ACP1 leads to a pleiotropic respiratory deficient phenotype.
Spatial joins are one of the most important operations for combining spatial objects of several relations. In this paper, spatial join processing is studied in detail for extended spatial objects in twodimensional data space. We present an approach for spatial join processing that is based on three steps. First, a spatial join is performed on the minimum bounding rectangles of the objects returning a set of candidates. Various approaches for accelerating this step of join processing have been examined at the last year's conference [BKS 93a]. In this paper, we focus on the problem how to compute the answers from the set of candidates which is handled by the following two steps. First of all, sophisticated approximations are used to identify answers as well as to filter out false hits from the set of candidates. For this purpose, we investigate various types of conservative and progressive approximations. In the last step, the exact geometry of the remaining candidates has to be tested against the join predicate. The time required for computing spatial join predicates can essentially be reduced when objects are adequately organized in main memory. In our approach, objects are first decomposed into simple components which are exclusively organized by a main-memory resident spatial data structure. Overall, we present a complete approach of spatial join processing on complex spatial objects. The performance of the individual steps of our approach is evaluated with data sets from real cartographic applications. The results show that our approach reduces the total execution time of the spatial join by factors.
In order to find further genes of the mitochondrial fatty acid synthase, we searched the genome of Saccharomyces cerevisiae for sequences that are homologous to conserved regions of bacterial fatty acid synthase genes. We found the gene products of ORF YKL055c (EMBL Accession No. X75781) and of YOR221C (EMBL Accession No. X92441) to be homologous to bacterial 3-oxoacyl-(acyl carrier protein) reductases and to malonyl-CoA:ACP-transferases, respectively. We disrupted these two genes which in both cases led to a respiratory deficient phenotype, as is the case for the genes encoding a mitochondrial acyl carrier protein and a beta-ketoacyl-ACP synthase. We propose to call the above mentioned genes OAR1 [3-oxo-acyl-(acyl carrier protein) reductase] and MCT1 (malonyl-CoA:ACP transferase). They are presumed to be part of a type-II mitochondrial fatty acid synthase, a relic of the endosymbiontic origin of mitochondria, delivering substrates for phospholipid re-modelling and/or repair.
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