Introduction: Chronic kidney disease (CKD), diabetes and cardiovascular disease are harmful chronic diseases that commonly occur together. Methods : present study was done in Amaltas medical college and index medical college, indore , m.p.. We have assessed serum creatinine urea and lipid profile level in Chronic renal failure patients. Results: we have found a highly significant change in serum Urea, uric acid and lipid profile in Subjects in comparisons to control Conclusion: Chronic renal failure is positively associated with deranged lipid profile and a great risk of cardiac diseases.

Introduction: Cardiovascular diseases (CVD) are known as important reasons of the increased morbidity and mortality observed in patients with chronic renal failure (CRF). The association of serum Interlukin-6 , homocysteine as well as other cardiovascular risk factors in relation to existence and cause of CVD were investigated. Method: In this study 200 CRF patients were recruited and further stratified into group with Male and Female as case groups. Those without renal failure were assigned as control group (n=200). Results: The patients with CRF showed a significant increase in plasma levels of Cpk-MB homocysteine and C-reactive protein (CRP) compared to control. The positive association were observed between homocysteine, Urea and Hs-CRP, IL_6 . It shows a significant Association of parameters in CRF . Conclusion: The results demonstrated elevation in plasma values IL-6 , homocysteine and HS-CRP in patients with CRF . However, these modifications may be lead to atherosclerosis and consequence CVD event. These parameters may be important with respect to the high morbidity and mortality of CVD found in patients with CRF.

Background: Cardiovascular disease (CVD) is consists of a variety of heart disease, illnesses and events that impact the heart & circulatory system, including high blood pressure & coronary artery disease (CAD). Vitamin D is one of the fat soluble vitamins also known as sunshine Vitamin due to its synthesis in the body following exposure to ultraviolet (UV) B rays. The aim of the study is to find the status of Vitamin D & there relation to Acute Coronary Syndrome. Materials and Methods:The present study included 50 cases of diagnosed acute coronary artery disease patients aged between 20 to 60 years and 50 apparently healthy controls and TMT negative matched for age and sex. Serum vitamin D was the measurement by ELISA method. Study Design: Prospective Observational Study. Results: The present study showed that significantly decreased levels of serum vitamin D (p<0.001) in acute coronary syndrome patients as compared with healthy controls. Conclusion: Decreased levels of vitamin D are a risk factor for the acute coronary syndrome, and also novel marker of CHD.