A new heterocyclic ligand (1,5-dimethyl-2-phenyl-4-(pyrimidin-2- yldiazenyl)-1,2-dihydro-3H-pyrazol-3-one, was synthesized by the diazotization of 2- (chlorodiazenyl)pyrimidine, and coupling with antipyrine to produce a new azo dye in an alkaline alcoholic solution under optimized experimental conditions (Azo-pyrm-Ap) (pyrimidin-2-yldiazenyl) ligand. and react with 1,10-phenanthroline, Ferric(II), Cobalt(II), Nickel(II), Copper(II), Zink(II), and Merrcury(II) ions were used to build the structure of mixed-ligand Tatradentate complexes. They confirmed all that by 1H- NMR,UVevisb, Fesem, XRD (DSC-TG) thermal analysis, Inferred- IR Magnetic susceptibility, The(C.H and N) analysis, molar conductance, and atomic absorption are all examples of spectroscopic techniques. The isolated solid complexes have been to have identified the formula in general [M (L)(phen) Cl] and [M (L)(phen)(H2O)] Cl, For prepared complexes, conductivity measurements revealed a [1:1] electrolyte. for Fe(II) and non-electrolyte for the Ni(II), Co(II), Zn(II), Cu(II), and, Hg(II) complexes. assemblages According to the spectral and analytical results, this ligand acts as a Bidentate chelating agent, with all metal ions having a coordination number of six. Finally, biological activity of the synthesized ligand and metal complexes against bacterial species was evaluated., Staphylococcus aureus is a Gram positive bacteria, and Escherichia coli, Pseudomonas aereuguinosa, and Klebsiella pneumoniaea are Gram negative bacteria. and it was found that these compounds have different inhibitory activity on bacteria growth.

A new heterocyclicligand 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)diazenyl)anthracene-9,10-dione. was synthesized by the diazotization of 2-Aminonthracene 9,10-dione coupling with Antipyrine in alkaline alcoholic solution under suitable optimized experimental conditions to yield a new azo dye(Azo-Anthq-Ap) . Then React mixed(Azo dye ligand with 1,10-phenanthroline complexes has been Prepared Fe(II), Co(II) Ni(II), Cu(II) , Zn(II), and, Hg(II) ions. They confirmed by 1 H-NMR,UV-visb,XRD, thermal analysis (TG, DSC).FT-IR spectroscopic methods, magnetic susceptibility, elemental analysis, atomic absorption, and molar conductance. The isolated solid complexes are found to have the general formula [M (L)(phen) Cl]. And [Fe (L)(phen)(H2O)Cl] Cl,conductivity measurements for prepared complexes showed [1:1] electrolyte for Fe(II), and non-electrolyte for the Co(II) Ni(II), Cu(II), Zn(II), and, Hg(II) complexes. The spectral and analytical data revealed that this ligand behaves as a Bidentate chelating agent and coordination number of all metal ions were found to be Six Shape.. Finally The synthesized Ligand and metal complexes were screened for their Antibacterial activity against bacterial species, one Gram positive bacteria (Staphylococcus aureus) and three Gram negative bacteria Escherichia coli, Pseudomonas aereuguinosa and Klebsiellapneumoniaea., it was found that these compounds show different activity of inhibition on the growth of the bacteria.