Background: Natural oil is an aromatic by-product of highly volatile plants. It can be easily extracted from a variety of natural sources using a variety of distillation processes due to its volatility. Oregano oil is a substance derived from the oregano plant, also known as Origanum vulgare. Objectives: The purpose of this study was to determine the physicochemical properties of oregano oil and to relate them to its chemical composition. Moreover, to examine its antibacterial activity against urinary tract pathogens. Materials and Methods: Commercial natural oregano oil (purity ≥98%) was obtained from Bluray food products operating under the brand name Bluray Food Products. The physico-chemical characteristics of oregano oil were determined using different techniques. GC-MS was used to analyze the chemical properties of oregano oil as well as analysis of saponification value, peroxide value, p-Anisidine value, pH value, and organoleptic properties (color, odor, consistency, nature, and solubility) were performed. Results: According to the results, GC-MS identified 66 different chemicals in oregano oil, accounting for 100% of the overall composition. It was found that oregano oil has a saponification value of 187.94 mg KOH/g, a peroxide value of 6.22, and a P-Anisidine value of 3.645. In addition, the oil of oregano was found to have inhibitory activity against all uropathogenic bacteria tested. E. coli has an inhibitory zone of 29 mm, P. aeruginosa 27 mm, K. pneumoniae 20 mm, P. mirabilis 22 mm, E. aerogenes 21 mm, E. faecalis 21-mm, A. baumannii 22-mm, N. gonorrhoeae 24-mm, S. aureus 26 mm, and S. epidermis 20-mm. Conclusion:Based on these results, it can be concluded that oregano oil was found to have optimal antibacterial activities against all tested urinary pathogenic bacteria.

Cinnamon oil is derived from the leaves of the cinnamon tree, the essential oil of the plant is extracted by steam distillation, while its bark is used to make cinnamon spice. The present study was conducted to isolate the most important bioactive compounds from cinnamon oil extracted from South India. The thin-layer chromatography (TLC) combined with high-performance liquid chromatography (HPLC) were used to determine and estimate the isolates obtained. It found that the organic phase's highest retention time was 5.433, and the peak area percentage was 88.8 %. The organic phase sample had a high peak area percentage, indicating that there was a lot of bioactive chemical in it. The broad absorption band at 3270 cm-1 is due to the (-OH) group, 1670 and 1623 cm-1 to the C=C group, 1449 and 1381 cm-1 to the (-C-H) group, and the band at 1120 cm-1 to the (-C-O) group. A pseudo molecular ion peak at m/z 275 for a [M+H] +. This study resulted in finding a peak in the positive mode mass spectra, indicating a molecular weight of 274 and the molecular formula of C15H14O5.1H 13CNMR investigations verified the presence of phenol hydroxide groups, two aromatic ring systems, methylene groups, and a phenoxy carbon in the chemical composition of the compound. Moreover, the composition is quite similar to catechins, and this chemical is separated from the organic phase of cinnamon oil. The potent inhibitory activity of the newly synthesized catechin antagonist against S.aureus and E.coli was found to assess cell death by detection of DNA fragments using agarose gel electrophoresis and SEM analysis.

Urinary tract infection is one of the most common infectious diseases and has a high financial burden on society. The occurrence of urinary tract infection acquired by the population is higher in young women, almost half of all women will have at least one UTI episode during their lifetime, and about 1 in 3 women will have at least one UTI episode at the age of 24 years. Urinary tract infection increases with age for both sexes. It is estimated that 10 percent of men and 20 percent of women over 65 years of age have bacterial symptoms. Worldwide, Community-associated UTI (CAUTI) prevalence is 0.7% and the main risk factors are age, sexual activity, history of urinary tract infection, and diabetes. UTI is caused by Gram-negative and Gram-positive bacteria, where more than 95 % of UTI cases are caused by bacteria. Gram-negative organisms, primarily from the Enterobacteriaceae family, are responsible for UTI. It includes Escherichia coli (74.20 %), Enterococcus spp (5.30 %), Staphylococcus saprophyticus (1.40 %) Pseudomonas spp. (3.20 %), Klebsiella pneumoniae (6.20 %), and Proteus mirabilis (2.00 %) are among the bacteria that cause UTIs, with other bacteria accounting for 8.70 % .The aim of this review is to provide a summary and critical evaluation of the published evidence about the etiological agents of urinary tract infection.

Cinnamon is known for its antimicrobial activity and the aim of this study was to investigate the effect of its essential oil against ten of the multidrug-resistant uropathogenic by agar well diffusion assays.  The diameters of the inhibition zone to the Cinnamon oil were 27 mm for S. aureus, 24 mm for E coli,    20 mm for P.aeruginosa,   22 mm for K.pneumoniae, 23 mm for E.aerogenes & P. mirabilis,    24 mm for E. faecalis, and   27 mm for N.gonorrhoeae, A.baumanni, S.epidermis. In this study, the antimicrobial effects of the cinnamon essential oil are evaluated by determining the minimum inhibitory concentration (MIC), the inhibition zone, and minimum bactericidal concentration (MBC). Cinnamon was the most effective agent in inhibiting A.baumanni, N.gonorrhoeae, S. epidermis, E. faecalis and E. coli with the lowest MIC (0.0313%) while S.aureus, E. aerogenes and P. aeruginosa with MIC (0.125%) while P. mirabilis was 0.0625% in our study. The MBC was 0. 25% for A.baumanni, 0.5 % for N, gonorrhoeae, S. epidermis, E. faecalis, and K. pneumonia, while 1% S.aureus, E. aerogenes, P. mirabilis, E. coli, and P. aeruginosa.