This study aimed to identify lifestyles and their relationship with the self-esteem of female adolescents who lost their mothers. The sample of the study consisted of 58 female adolescents who lost their mothers during the academic year 2019/2020. To achieve the objectives, the study developed two scales; the lifestyles scale and the self-esteem scale. These scales were applied to the participants as a questionnaire. Validity and reliability for both scales were obtained. The results showed that the most common lifestyle among female adolescents who lost their mothers was the socially useful style, and the level of self-esteem among female adolescents who lost their mothers was moderate. The results also showed that there were no statistically significant differences in lifestyle and self-esteem due to the two variables of age at loss and birth order. The results also showed that there was a statistically significant positive correlation between the total score of the self-esteem scale and both dominating style and the socially useful style. Keywords: Adolescent, lifestyle, orphaned, self-esteem