No abstract

Carbohydrates are the primary macronutrients that humans consume to support the body’s need for a source of energy. Monosaccharides like glucose are the simplest form of carbohydrate that is readily absorbed in the bloodstream, followed by disaccharides like sucrose, which are converted into glucose prior to absorption and energy release. To evaluate the absorption, distribution, and absorption kinetics of glucose, sucrose, and a combination of the two in the bloodstream, a preclinical study was conducted in Sprague-Dawley (SD) rats showing instant and sustained energy release through the change in blood glucose level after intake of the test product. The data of blood glucose tested using a glucometer were analyzed and evaluated using a regression method. The comparison study determines whether monosaccharides, disaccharides, or a blend of both have an impact on absorption kinetics and sustenance of blood glucose levels. The result showed glucose was absorbed in the bloodstream at a faster rate as early as 60 seconds (onset time) than sucrose and peaked within 30 minutes thus providing instant energy. Additionally, sucrose and its combination with glucose maintained blood glucose levels for a longer duration compared to glucose alone with a lower regression slope of 0.744 (sucrose) vs. 1.247 (glucose). Sucrose and its combination with glucose providing slow and steady energy release upto 4 hours. In conclusion, glucose provided instant energy, while sucrose and its combination with glucose provided sustained energy release after intake.

Objective: The current research is an attempt to evaluate the wound healing activity of Electrohomeopathic drug Green electricity (GE) in Wistar rats. No data have been reported till date on the wound healing effect of GE. Hence the present research focuses on the scientific investigation of the wound healing activity of GE in rats. Methods: Excision and incision wounds were inflicted upon albino rats. In the excision wound model, the wound contraction, Scar residue, area and time of complete epithelization were measured subsequently on day 0, 3,6,9,12,15, 18 and 21 after inflicting the wound. Wound contraction was calculated as a percentage change in the initial wound size. In the incision wound model, the tensile strength was measured on the 10th post wounding day. Results: It was noted that the effect produced by the GE Showed significant wound healing (p<0.01) in all wound models when compared to the control group. In the case of the excision model, GE statistically increases the wound contraction rate and in the case of the incision model GE showed high tensile strength as compared to the control group. In both cases the epithelization period was significantly decreased as compared to control. Almost 100% wound protection was achieved by GE in 21 d as compared to control. Conclusion: GE (ointment) showed significant wound healing activity (p<0.01) in both the excised wound model and incision wound model in rats.