BACKGROUNDAntibiotic resistance pattern of CSOM has been changing according to geographical variation and differences in patient population. Increased and irrational use of broad spectrum antibiotics, as well as resistance in bacterial isolates, has become very common. Staphylococcus is one of the most important bacteria in CSOM and MRSA is a common pathogen in otologic diseases. Continuous and periodic surveillance of MRSA is necessary to reduce the spread of antibiotic resistant pathogens in CSOM cases.