The problem of mixed convective flow of a couple stress fluid in a vertical channel in the presence of first order chemical reaction and heat generation/absorption is studied. Two walls of the channel are considered with asymmetirc heating conditions along with flux boundary conditions on temperature and concentrations. The governing nonlinear differential equations are solved numerically. The effect of physical parameters like couple stress, heat generation/absorption, chemical reaction, thermal buoyancy and concentration buoyancy are evaluated numerically. Also heat transfer parameters such as Nusselt number, Sherwood number and skin friction factors are analyzed.