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Most dental procedures require the use of local anesthetics. The Morpheus™ anesthetic computerized injector (Morpheus™ injector) provides painless needle insertion and satisfactory anesthesia with lower volumes of local anesthetic. The use of the intraseptal Alveolar Crest Spongy Bone Area (ACSBA) anesthesia technique with the Morpheus™ injector is an alternative to painless treatment. Thus, the objective of this study was to evaluate the anesthetic properties of the ACSBA technique using two different anesthetics, lidocaine and articaine. This randomized, split-mouth, triple-blind clinical trial included 31 volunteers who required restorative treatment of the lower first molars. In two sessions, 2% lidocaine with 1:100000 epinephrine and 4% articaine with 1:100000 epinephrine solutions were administered using the ACSBA technique. Patient physical parameters, pain perception, and degree of anxiety as well as anesthetic properties were evaluated. There were no statistically significant differences between the groups or time points for systolic (p = 0.928) and diastolic (p = 0.450) blood pressure or heart rate (p = 0.624). Moreover, there were no statistically significant differences between the treatments for needle insertion (p = 0.741) or anesthetic deposition (p = 0.810). Both of the anesthetic protocols had a 9.7% failure rate. The Mann-Whitney test showed no statistically significant differences between the groups in anesthesia latency (p = 0.758) or duration (p = 0.791). Articaine and lidocaine were safe drugs, and there was no change in their influence on the evaluated physical parameters. Articaine was similar to lidocaine for anesthesia duration with means of 70.7 and 61.1 min, respectively. The intraseptal ACSBA anesthesia technique was effective, provided sufficient anesthesia duration to perform medium-term dental procedures with articaine and lidocaine, and produced painless anesthesia that provided greater patient comfort.

Introduction: Anxiety is one of the components of patient stress in the dental office and is recognized as one of the main factors that negatively affect treatment. The use of phytotherapics represents an option for the control of conventional anxiety. Thus, the objective of this study is to evaluate the effect of the association between Valeriana officinalis L. and Humulus lupulus L., on the control of anxiety in patients submitted to bilateral mandibular third molar exodonts included. Materials and Methods: Randomized, controlled, double-blind, splith-mouth, cross-over clinical trial involving a sample of 43 volunteers, after diagnosis and indication for bilateral exodontics of the included mandibular third molars, asymptomatic and in similar surgical positions and difficulties. A single oral dose of Valerian and Hops (500 mg and 120 mg, respectively) or placebo (starch) was administered randomly and crossover 1 hour before each surgical procedure. Anxiety level was assessed by physiological parameters such as heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) and oxygen saturation content (SpO2), in three distinct phases: Phase I (baseline); Phase II (intervention day) and Phase III (return visit). Results: The herbal medicine promoted a statistically significant reduction of the PAS and PAD levels (two-way Anova with Holm-Sidak correction, p<0.05) at all times of surgery when compared to placebo. The phytotherapic generated a lower degree of anxiety (Fisher's Exact test) in the evaluations of the researcher (p<0.0001), operator (p<0.0001) and patient (p<0.0001). There were no reports of retrograde amnesia and 19 patients (51.4%) reported post-surgical muscle relaxation after use of the herbal medicine. Conclusion: The association of Valerian with Hops promotes a reduction of pressure levels, anxiety levels and has no side effects, in adult patients submitted to exodonties of the mandibular third molars included.