ABSTRAKPenelitian ini bertujuan untuk menguji efektifitas antibakteri ekstrak etanol daun afrika (Vernonia amygdalina Delile) terhadap bakteri Staphylococcus aureus dan Escherichia coli menggunakann metode difusi agar. Daun afrika asal Papua banyak dimanfaatkan di masyarakat lokal untuk pengobatan luka dan digunakan untuk menghilangkan jerawat. Daun afrika mengandung flavonoid, tannin, saponin, dan terpenoid. Pengambilan sampel dilakukan di Kota Jayapura, Papua. Lokasi penelitian dikerjakan di Laboratorium Program Studi Farmasi dan Laboratorium Biologi, Universitas Cenderawasih. Prosedur kerja meliputi pembuatan simplisia daun afrika, ekstraksi daun afrika, dan uji efektivitas antibakteri. Hasil pengujian aktivitas antibakteri pada konsentrasi paling rendah menunjukkan bahwa ekstrak daun afrika dapat menghambat pertumbuhan bakteri S. aureus dan E. coli sebesar 6,69 mm dan 6,52 mm. Berdasarkan hasil analisis Beda Nyata Jujur (BNJ) tidak ada perbedaan yang nyata antara daya hambat pada masing-masing konsentrasi ekstrak daun afrika terhadap bakteri S. aureus dan E. coli, sehingga dengan konsenterasi paling kecil (100 μg/mL) telah memberikan aktivitas antibakteri terhadap bakteri S. aureus dan E. coli. ABSTRACT The aim of this study was to investigate the antibacterial activity of Vernonia amygdalina Delile (daun afrika) extract from Papua against Staphylococcus aureus and Escherichia coli by using agar diffusion methods. Afrika leaves from Papua is widely utilized by local people, one of them to the treatment of acne and wound healing.Previous researches demonstrated that daun afrika contained flavonoids, tannins, saponins, and terpenoids. In this study, sample was collected from Jayapura, Papua. The research was carried out at PHARMACY: Jurnal Farmasi Indonesia p-ISSN 1693-3591 (Pharmaceutical Journal of Indonesia) e-ISSN 2579-910X Vol. 15 No. 02 Desember 2018 149Cenderawasih University. The procedures of this study included preparation of daun afrika crude drugs, extraction, and antibacterial activity test. The research result showed that the extract of daun afrika inhibited the growth of Staphylococcus aureus and Escherichia coli at concentration of 100 μg/mL with inhibition zone diameter of 6.69 and 6.52 mm, respectively. The least significant difference test showed there was no different inhibition zone in each concentrations of daun africa extract against S. aureus and E. coli.

Kampung WulukubunArso XIV, Distrik Skanto Kabupaten Kerombanyak ditumbuhi daun gatal yang bermanfaat sebagai obat tradisional sebagai antinyeri, mengurangi rasa capek, dan mengurangi pegal-pegal. Daun gatal banyak terdapat di kampung tapi sering sekali hanya dibiarkan kering, layu, mati, bahkan dibuang. Padahal nilai dari daun ini sangat besar jika dikembangkan tidak hanya lembaran daun gatal tetapi sebagai produk farmasi. Tujuan dari kegiatan ini adalah melakukan sosialisasi dan membuat sediaan topikal salep daun gatal di kampung Wulukubun Arso XIV Kabupaten Keerom Papua. Kegiatan ini dilaksanakan dengan melakukan persiapan di kampus/ administrasi, menjalin kerjasama dengan mitra, instansi terkait, kegiatan hari H di kampung, evaluasi, laporan, dan publikasi. Hasil yang diperoleh dari kegiatan ini adalah 7,4% peserta pernah mengikuti kegiatan yang sama. Sebanyak 88,9% peserta memperoleh manfaat dari kegiatan ini dan 70,4% berkomitmen akan membantu orang lain dalam menyebarluaskan informasi penting yang mereka dapat pada waktu kegiatan ini.

Zodia (Evodia suaveolens Scheff) and lemongrass (Cymbopogon citratus) are native Indonesian plants with repellant activity against mosquitoes and insects. The purpose of this research were to formulate and evaluate the repellant activity of zodia-serai lotion against Aedes aegypti and determine the protection power of three formulas of lotion. The method used in this research including steam distillation of essential oil from zodia leaves and lemongrass, formulation and evaluation of lotions, power protection test, and data analysis. The result of this research showed that lotion had acidic pH of 5, and they were stable without separation after stability evaluation with centrifugation. The most effective repellant activity of the lotion was exhibited at 0 hours with 100% of repellency. The best combination of essential oils of zodia (Evodia suaveolens Scheff) and lemongrass (Cymbopogon citratus) as Aedes aegypti repellent was at ratio of 7:3.

Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk memberikan edukasi tentang bahaya limbah anorganik bagi lingkungan dan kesehatan serta memberikan pelatihan cara pengolahan limbah anorganik berupa kain perca sehingga memiliki nila guna dan nilai ekonomi. Pengabdian ini dilakukan di Desa sumber Baru Kecamatan Lampung Tengah karena berdasarkan hasil prasurvei dari 4 penjahit rumahan di Desa Sumber Baru tersebut belum tahu cara memanfaatkan limbah kain perca. Metode yang dilakukan adalah dengan memberikan edukasi bahaya limbah onorganik dan memberikan pelatihan pengolahan limbah anorganik dari kain perca kepa masyarakat. Berdasarkan hasil kegiatan tersebut masyarakat menjadi peduli terhadap lingkungan dengan mengolah limbah anorganik kain perca menjadi keterampilan yang memiliki niali guna dan nilai ekonomi, seperti bros dan bandana.Patchwork Cloth Skills Training to Reduce Inorganic WasteAbstractThe purpose of this community service activity is to provide education about the dangers of inorganic waste to the environment and health and to provide training in how to treat inorganic waste in the form of patchwork so that it has value and economic value. This dedication was carried out in Sumber Baru Village, Central Lampung District because based on the results of a survey of 4 home tailors in Sumber Baru Village, they did not yet know how to utilize patchwork waste. The method used is to educate the dangers of inorganic waste and provide training in the treatment of inorganic waste from patchwork to the community. Based on the results of these activities the community becomes concerned about the environment by treating patchwork inorganic waste into skills that have value and economic value, such as brooches and bandanas.

Drymis sp. stem bark from Papua widely utilized by local people especially in Sougb Tribe from Sururey Distric Pegunungan Arfak West Papua, one of them is used to increase the stamina of the body. The aim of this study was to investigate the tonic effect of Drymis sp. stem bark of Ratus norvegicus. Ratatory exhaustion method was used to the tonic effect. Selected rats (30) were divided into 6 groups, each consisting of 5 rats. Tested extract was administrated oraly one dose to the rats. Group I, II and III was given the ethil acetat fraction of Drymis sp. stem bark 10mg/kg body weight, 30mg/kg body weight and 50mg/kg body weight consecutively. Group IV was given CMC-Na 0,5% (as negative control). Goup V was given caffein 15 mg/kg body weight (as positive control) and Group VI as a control. The total swimming period until exhaustion was measured and use as index of swimming capacity. Research result show that the highest dose 50 mg/body weight of the tested fraction the longer swimming time and with better stamina. The result of One Way ANOVA test showed that there was a significant difference between treatment group, followed by tukey test, tukey result obtained the ethil acetat fraction and negative control (CMC Na) showed that there was significant difference, and there is no real difference between between treatment group and positive control.   Key words: Drymis sp, Papua, tonic effect, rats.