Background: FNAC is rapidly emerging as a useful tool in the diagnosis of metastatic lesion of lymph nodes. FNAC not only confirms or excludes metastasis in a case of a known primary malignancy but, also, in most cases helps to detect occult primary malignancy. Aim of present study was to determine the frequency of metastatic lesions of lymph nodes.Methods: This retrospective study was done of all metastatic lymph node lesions reported on FNAC, in the department of pathology, NSCB medical college, Jabalpur from January 2014 to December 2014 (One Year).Results: Total cases of 400 lymph node aspiration were done, of which 120 cases were clinically suspicious of metastasis. Cytology results were positive for metastasis in 97 cases (80.8%). The most common site of aspiration was cervical lymph nodes (75.2%). Maximum number of cases of metastasis were in 51-60 years age group with male predominance (male:female 2.6:1). The most common metastasis was squamous cell carcinoma seen in 74 cases (76.2%), followed by metastatic mammary carcinoma (10.3%), remaining were adenocarcinoma, undifferentiated carcinoma, malignant melanoma, papillary thyroid carcinoma and transitional cell carcinoma.Conclusions: FNAC is a rapid, safe and cost-effective technique. It gives early and accurate results with minimal invasion and reduces the need for surgical biopsies, thus saves cost and time to reach the final diagnosis. It is therefore concluded that FNAC is a useful tool in diagnosing metastatic lesions of lymph nodes with a good certainty.

Introduction: Adrenal myelolipoma with extramedullary hematopoiesis (EMH) is an exceedingly rare entity with very few cases reported in the literature. We present a rare case of adrenal myelolipoma with EMH. Case report: A 48-year-old man with the previous history of splenectomy for hereditary spherocytosis was presented with 12 × 12 cm right adrenal tumor and underwent laparoscopic adrenalectomy. The histopathological features confirmed the diagnosis of adrenal myelolipoma with EMH. Conclusion:In any patient with a history of chronic hemolytic anemia and adrenal mass, it is imperative to consider EMH as a possible diagnosis.

Objective: This study was conducted to formulate locationwise radiologic diagnostic algorithms and assess their concordance with the final histopathological diagnosis of intracranial mass lesions to evaluate their utility in a rural setting where only basic facilities are available. Material and Method: In present study seventy two cases were analyzed.Histopathological evaluation was done from biopsy sample sent in formalin, tissue processing was done by standard procedure, tissue sections were routinely stained by H&E, immunohistochemical examination was performed in case of histopathological discrepancies. Radiological findings were correlated with histopathological diagnosis and concordances were calculated. Statistical Analysis: Frequencies and crosstabs were used for calculation. Result: This was a study of seventy-two patients with age ranging from 9months to 65 years. In these entire 72 cases, male patients were 42(58%), female patients were 30(42%). M: F was 1.38:1. Most of patient presented with headache, and frontal lobe was the most common location. In all these lesions, 88.8% cases were neoplastic lesions. Among all neoplastic lesions, 52.7% were malignant tumors and 34.7% were benign tumors. Among all malignant tumors, Astrocytoma was the most common malignant tumor.Meningioma was the second most commonly encountered lesion. In the present study radiological and histopathological correlation was present in84.7% of cases. IHC was performed wherever needed, to support diagnosis. Conclusion: Radiological investigations are reliable diagnostic tools for space occupying central nervous system lesions, but histopathology is still the gold standard. So multidisciplinary approach is the ideal approach for space occupying lesions of central nervous system.

Fine Needle Aspiration of the liver is a simpler technique and is reported to yield higher positivity in patients with hepatic malignancy as compared to core biopsy. Fine needle aspiration cytology has the advantage of causing significant less discomfort and a very low risk of complication. Of all the radiological procedures the ultrasound is most suited for fine needle aspiration cytology as real time images can be obtained and it prevents the perforation of gall bladder, colon and blood vessels, Ultrasound has higher level of practicality, requires no ionizing radiation and is widely applicable as compare to computerised tomography scan. Aim of the present study is to establish role of Ultrasound guided Fine Needle Aspiration in diagnosis of liver mass lesions. Methods : We have performed UGS guided FNAC on 42 suspected cases of liver mass lesion. Detail history, clinical examination was done and consent was taken from patient after explaining the procedure to them. Bleeding time, Clotting time and Prothrombin time were done prior to procedure. All patients with liver mass lesion diagnosed on radiology were included in the study. Under all aseptic precaution Ultrasound guided FNAC was done from liver mass lesion using 26 gauge lumbar puncture needle. The material obtained in the needle was expelled onto glass slide and smear was made by opposition technique. Results: Of 42 aspirates from liver, 13 were diagnosed as hepatocellular carcinoma, 23 were diagnosed as metastatic carcinomas. Attempt of grading and study of cellular patterns was done in hepatocellular carcinoma. Of 23 cases of metastatic carcinoma, in 11 cases primary site could be demonstrated. In 12 cases primary site could not be determined. 18 were adenocarcinomas and 5 were undifferentiated anaplastic carcinoma. Conclusion: Ultrasound guided Fine Needle Aspiration of liver mass is safe ,cost effective technique in localizing Liver lesion and acquiring adequate material for preoperative diagnosis of mass lesion of liver

Introduction: All of the imaging techniques have advantages and disadvantage in various parts of the body. In intraabdominal lesion ultrasonography guided FNAC has advantage over computerised tomography guided FNAC because CT is very costly and not freely available. CT gives high dose of radiation and therefore should not be used in pregnant women and in small children whereas ultrasonography has no radiation effects and hence can be safely used in these cases. Mobile version of CT is not available and therefore it cannot be used in faraway places whereas ultrasonography machine is mobile. Thus, with localization by ultrasonography diagnosis of the malignancy and staging can be accomplished through FNAC. Method: Total of 100 cases who came for FNAC of intraabdominal masseswere included in the study, irrespective of their age, sex or possible nature of mass. Ultrasound guided Fine needle aspiration was done in all.The aim of the present study was to assess the feasibility of ultrasound guided Fine needle aspiration cytology of routine procedure for detection of abdominal lesion. Result: Total of 100 cases were studied. In the 80(80%) cases, aspirates were positive for malignancy and in 17(17%) cases were negative for malignancy. There were 3% false negative cases encountered. There were no false positive cases. Ultrasound was used for mass localization. In 80 positive cases of malignancy, 36 cases from liver, 10 from lymph node, 7 from gall bladder, 6 from stomach, 6 from ovary, 3 from urinary bladder, 1 from pancreas, I from uterus, 3 from miscellaneous sites. Conclusion: Percutaneous fine needle aspiration cytology is reliable method of diagnosing the various pathological lesions of abdomen. Its diagnostic accuracy is further increased when performed under Radiological guidance. Of all modalities of guidance at present is the most suitable.