Introduction: Traumatic brain injury is one of the most common causes of disability, death and intensive care unit (ICU) hospitalization worldwide. Each year an estimated ten million people experience brain injuries. All kinds of stimulation can effectively affect the brain, especially the reticular activation system. The aims to determine the effect of family-centered sensory stimulation by comparing the experimental, placebo and control groups. Method: This study used a randomized controlled trial involving comatose patients with brain injury. The investigators concluded that 30 patients were needed for each study group. Initially, an allocation protocol was developed using the permutation block randomization technique. Result: The one-way ANOVA results illustrated that the differences between groups regarding GCS scores on the first day and the second day of the intervention were not statistically significant, whereas on days 3-7, the differences were statistically significant. The results of this study indicate that early family-centered stimulation is more effective than sensory stimulation in correcting LOC among comatose patients with traumatic brain injury. Conclusion: Family-centered stimulation was effective in improving levels of consciousness among comatose patients from day three to day seven.

Introduction : Nurses are one of the health workers who provide health services who encounter various conditions that can cause stress. Nurses who feel the stress certainly have an impact on the quality of health service that they are giving, therefore the stress management to overcome the stress is needed. One of the stress management that is cheap and accessible for nurses anywhere and anytime is humor. Method: This study uses a systematic review method. Result: Humor is a way that can change the psychological condition of individuals. Ways of this humor therapy is smiling and laughing. Nurses can smile and laugh by reading comics, joking, watching comedy filmsand or can be in the form of a fictional story told by a friend who is considered funny, and so on. In this study, the nurses believed that humour provides an opportunity for change. In relation to this, the results showed that the consequences of humour can range  from revival to exhaustion. In addition to enabling mental rest, humour helps change patients’ perspectives regarding their health condition. Conclusion: Stress conditions experienced by nurses arise due to workload and so on. This will have an impact on nursing care services that will be provided to patients in the hospital. Humor is one of the most effective stress management tools to reduce stress. Humor that nurses do is just enough to smile and laugh, of course this method is very easy to do and does not require expensive costs.

Introduction: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. The leading cause of death worldwide is responsible for 1.5 million deaths each year. The cause of tuberculosis infection is the tubercle bacillus discovered by Robert Koch in 1882. The organism causing it is Mycobacterium tuberculosis.The spread of new cases is divided in several regions including Southeast Asia and Africa, which are the regions that have the biggest contribution to the prevalence of tuberculosis. So it takes pillars and components of TB control that cover all lines. Method: This study aims to discuss the potential of herbal plants spread in Indonesia as herbal medicines that have the potential to treat tuberculosis infection. This study uses a literature study method which prepares the same as other research, but the sources and methods of data collection are by taking data from the library, reading, taking notes, and processing research materials. Result: One of the components that are currently being developed in TB infection intervention methods is the development of herbal medicines for tuberculosis control. The herbal medicines used come from garlic (Allium sativum), Centellaasiatica, beluntas leaves, Hibiscus rosasinensis L., Boechmeria virgate (Forst) Guill, tobacco leaves, Morindacitrifolia L., Javanese wood bark, Spondiaspinnata (Lf)Kurz. Conclusion: The herbal medicinal ingredients contain major chemicals such as alicin, ajoene, asiaticoside, asiatic acid, madecassic acid, and madecassoside, alkaloids, flavonoids, tannins, saponins, phenolic, and triterpenoids which have the ability to have a bactericidal effect to kill the Mycobacterium tuberculosis bacteria.