Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectomebased classification mostly relies on traditional convolutional neural networks using input connectivity matrices on a regular Euclidean grid. We propose a graph deep learning framework to incorporate the non-Euclidean information about graph structure for classifying functional magnetic resonance imaging (fMRI)derived brain networks in major depressive disorder (MDD). We design a novel graph autoencoder (GAE) architecture based on the graph convolutional networks (GCNs) to embed the topological structure and node content of large-sized fMRI networks into low-dimensional latent representations. In network construction, we employ the Ledoit-Wolf (LDW) shrinkage method to estimate the high-dimensional FC metrics efficiently from fMRI data. We consider both supervised and unsupervised approaches for the graph embedded learning. The learned embeddings are then used as feature inputs for a deep fully-connected neural network (FCNN) to discriminate MDD from healthy controls. Evaluated on a resting-state fMRI MDD dataset with 43 subjects, results show that the proposed GAE-FCNN model significantly outperforms several state-of-the-art DNN methods for brain connectome classification, achieving accuracy of 72.50% using the LDW-FC metrics as node features. The graph embeddings of fMRI FC networks learned by the GAE also reveal apparent group differences between MDD and HC. Our new framework demonstrates feasibility of learning graph embeddings on brain networks to provide discriminative information for diagnosis of brain disorders.

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GAN-generated deepfakes as a genre of digital images are gaining ground as both catalysts of artistic expression and malicious forms of deception, therefore demanding systems to enforce and accredit their ethical use. Existing techniques for the source attribution of synthetic images identify subtle intrinsic fingerprints using multiclass classification neural nets limited in functionality and scalability. Hence, we redefine the deepfake detection and source attribution problems as a series of related binary classification tasks. We leverage transfer learning to rapidly adapt forgery detection networks for multiple independent attribution problems, by proposing a semi-decentralized modular design to solve them simultaneously and efficiently. Class activation mapping is also demonstrated as an effective means of feature localization for model interpretation. Our models are determined via experimentation to be competitive with current benchmarks, and capable of decent performance on human portraits in ideal conditions. Decentralized fingerprint-based attribution is found to retain validity in the presence of novel sources, but is more susceptible to type II errors that intensify with image perturbations and attributive uncertainty. We describe both our conceptual framework and model prototypes for further enhancement when investigating the technical limits of reactive deepfake attribution.