Context:Intraoperative cytology and frozen section play an important role in the diagnosis of neurosurgical specimens. There are limitations in both these procedures but understanding the errors and pitfalls may help in increasing the diagnostic yield.Aims:To find the diagnostic accuracy of intraoperative cytology and frozen section for central and peripheral nervous system (PNS) lesions and analyze the errors, pitfalls, and limitations in these procedures.Settings and Design:Eighty cases were included in this prospective study in a span of 1.5 years.Materials and Methods:The crush preparations and the frozen sections were stained with hematoxylin and eosin method. The diagnosis of crush smears and the frozen sections were compared with the diagnosis in the paraffin section, which was considered as the gold standard.Statistical Analyses Used:Diagnostic accuracy, sensitivity, and specificity.Results:The diagnostic accuracy of crush smears was 91.25% with a sensitivity of 95.5% and specificity of 100%. In the frozen sections, the overall diagnostic accuracy was 95%, sensitivity was 96.8%, and specificity was 100%. The categories of pitfalls noted in this study were categorization of spindle cell lesions, differentiation of oligodendroglioma from astrocytoma in frozen sections, differentiation of coagulative tumor necrosis of glioblastoma multiforme (GBM) from the caseous necrosis of tuberculosis, grading of gliomas in frozen section, and differentiation of the normal granular cells of the cerebellum from the lymphocytes in cytological smears.Conclusions:Crush smear and frozen section are complimentary procedures. When both are used together, the diagnostic yield is substantially increased.
OBJECTIVES: To assess the oral health status and treatment needs of inmates of, District Jail Mathura. MATERIALS AND METHODS: A cross sectional study was carried out on the inmates (N=870) in the district jail of Mathura. Proforma related to general demographic information was filled by the examiner and the subjects were clinically examined using WHO 1997 "Oral Health Assessment Form
RESULTS:This study revealed that 92.5% of the inmates were male. 53.8% never visited the dentist & 87% never received any type of dental care during imprisonment. Prevalence of pro-mucosal lesion was 59.8%. Inmates had poor periodontal conditions and 79% inmates had dental caries with mean DMFT of 4.79.CONCLUSION: Periodontal disease, mucosal lesions and dental caries are major public health problem among the inmates, which require special attention and efforts from government and other organizations to meet their treatment needs.
Background: Malaria continues to be a prominent global public health challenge. This study tested the effectiveness of two service delivery models for reducing the malaria burden, e.g. supportive supervision of community health workers (CHW) and community mobilization in promoting appropriate health-seeking behaviour for febrile illnesses in Odisha, India. Methods: The study population comprised 120 villages from two purposively chosen malaria-endemic districts, with 40 villages randomly assigned to each of the two treatment arms, one with both supportive supervision and community mobilization and one with community mobilization alone, as well as an observational control arm. Outcome measures included changes in the utilization of bed nets and timely care-seeking for fever from a trained provider compared to the control group. Analysis was by intention-to-treat.
The immune system of cancer patient gets compromised because of cancer therapy, surgery, and malignancy and thus the probability of infection are increased than the general patients. Immunosuppression can expose cancer patients to serious complications which can lead to delay in diagnosis and unnecessary hospitalizations that may adversely affect the prognosis of the disease. Patients who received chemotherapy or surgery within the 30 days before novel coronavirus disease pandemic have more risk of infection than the patients who had not undergone chemotherapy or surgery.
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