Orbital cholesterol granuloma is a rare entity which can cause proptosis, diplopia and extraocular movement restriction. It is often mistaken for other entities such as epidermoid, dermoid cysts and lacrimal gland tumours. Here authors report a case of a 36- year-old male who presented with proptosis of right eye and diplopia on upward gaze. Computed Tomography (CT) scan showed an extraconal lesion in superotemporal compartment of right orbit with erosion of bony wall. On imaging findings, epidermoid and dermoid cysts were considered as probable diagnoses. On histology, the lesion showed cholesterol clefts, foamy and haemosiderin laden macrophages and foreign body giant cells. Lesion was diagnosed as cholesterol granuloma. While being very rare at this site, this lesion carries a good prognosis with complete surgical excision. Patient showed marked postoperative improvement and was asymptomatic at discharge.

Melanocytomas of the central nervous system are rare benign or intermediate grade localized melanocytic tumors. Despite its benign nature, it can follow a locally aggressive course with propensity to recur. We present the case of a 29 years old female who presented with a recurrent lesion in cervical spine and rapidly progressing quadriparesis. On examination, there was loss of power in right-sided extremities and reduction in sensations in left-sided extremities. Magnetic resonance imaging spine revealed a homogeneously enhancing intradural extramedullary dumbbell-shaped mass lesion at C4/5 level with extension through right C4 neural foramina to the extraforamina space, causing severe spinal cord compression. Intraoperatively, bluish-colored tumor was identified along with underlying hematoma. Gross total excision of the tumor was done. Tumor was received in the histopathology department in multiple black-colored fragments. Microscopically, a heavily pigmented tumor was seen with the sheets and nodules of polygonal cells with large nuclei and prominent nucleoli. Differentials considered were meningeal melanocytoma and malignant melanoma. On immunohistochemistry, the tumor cells showed diffuse positivity for HMB 45 and S100. Ki 67 index was around 1%. On radiological review, the tumor was fairly well circumscribed and did not infiltrate the adjacent tissues. There was no evidence of any lesions elsewhere in the body. Considering these features, the tumor was diagnosed with meningeal melanocytoma. Postoperatively, there was significant immediate improvement in quadriparesis and patient could walk with minimal support.

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Endometriosis is referred to the presence of functioning, ectopic endometrial tissue outside the pelvic cavity. Their occurrences after abdominal or pelvic surgeries especially cesarean section, at the site of scar incision, are documented. The patient experiences cyclical pain at the incision site related to the menstrual cycle. Imaging can be used to detect the lesion and medical management can be provided. However, in severe cases, total excision is recommended to avoid the chances of recurrence. Here, we present a case series of two cases of scar endometriosis after cesarean section, and both presented with cyclical pain in the abdomen. Medical management was provided for both cases.

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