Introduction: Incidence of infection after internal fixation of closed fractures is generally lower (1−2%). Aim of this study is to find out risk factors and identify the organism and their sensitivity to commonly used antibiotics in post-operative infected cases following internally fixed closed fractures. Material & Methods: 211 patients of all ages and both sexes underwent elective surgery for internal fixation of closed fractures by a single surgical team at our institute from September 2016 to September 2017. 18 of them developed post-operative infection and were retrospectively analysed. Presence of post-operative infection was diagnosed on basis of history, clinical examination, blood parameters and radiographs. Surgical site infection, superficial or deep, florid or low grade, early or delayed or late onset infection were defined as per existing literature. Microscopy, culture and sensitivity test was done on swabs obtained from discharge through surgical site or sinus tract or from deep tissues during surgical exploration under anaesthesia. Results: The post-operative infection rate in our study was 8.53% (18 cases out of 211). Males (n=14), age > 40 years (n=11), femur (n=9, 50%) especially proximal end (n=7), pre-operative hospital stay for > one week and increased duration of surgery of more than 60 minutes were most commonly affected. 5 out of 40 cases (12.5%) of closed reduction and 13 out of 171 cases (7.6%) of open reduction developed post-operative infection. The percentage of post-operative infection with plate, intramedullary nail, screw and bipolar prosthesis implantation are almost similar. Late onset (50%), superficial (61.11%) and low grade infection (77.78%) were more common than their counterparts. Staphylococcus aureus was the most common organism followed by Klebsiella pneumonae. Imipenem, ciprofloxacin& vancomycin were most common sensitive antibiotics. Imipenem showed sensitivity to gram negative organisms but Vancomycin, Co-trimoxazole, Cefoxitim and Linezolid were sensitive to Staphylococcus species including MRSA (Methicillin resistant Staphylococcus aureus). Ciprofloxacin was sensitive to both Staph species & gram negative organisms. 15 patients had at least one comorbidity and 8 patients had more than 2 comorbidities, anaemia being the most common. Conclusion: Knowledge of patient related clinical factors and commonly isolated organisms and their antimicrobial sensitivity patterns within a given hospital assists in prophylaxis and treatment of postoperative infection.

<p class="abstract"><strong>Background:</strong> Plantar fasciitis is one of the most common causes of heel pain. Various methods of treatment are available but no ideal treatment has been defined in literature. Corticosteroid (CS) injections are being used as a gold standard but studies have shown its short-term effects and various complications. Recently, platelet rich plasma (PRP) has been advocated as a newer treatment option. The main aim and objective of this study is to compare the two modalities of treatment regarding both pain and functional scores and their complications.</p><p class="abstract"><strong>Methods:</strong> This study was a prospective cohort study. Total 90 patients with chronic plantar fasciitis visiting orthopaedic outpatient department of Assam Medical College and Hospital, Dibrugarh from July 2018 to June 2019 were enrolled for the study after clearance from Institutional Ethics Committee and equally divided into two groups. Group A received PRP and Group B received CS injections. They were assessed with visual analogue scale (VAS) and foot and ankle ability measure (FAAM) score at day 0, at 1 month, 3 months and 6 months. Level of significance was set at p&lt;0.05.<strong></strong></p><p class="abstract"><strong>Results:</strong> The score on VAS and FAAM improved from baseline for both the groups. CS showed better results at 1 month and 3 months but at 6 months, results of PRP were better. 3 patients had recurrences in CS group.</p><p class="abstract"><strong>Conclusions:</strong> Corticosteroid injections provide immediate and short-term relief but PRP is beneficial with long term effects and without any complications.</p>