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Introduction. Langerhans' cell histiocytosis is an uncommon disease, with various radiological presentations. Its cause remains unknown, with the pathological hallmark being proliferation of Langerhans' cells. The spectrum of disease ranges from solitary bone lesions to multisystemic affection. Usually, the first diagnostic test performed is the plain radiograph, and the radiological findings may be hard to analyze. Differential diagnosis should include osteomyelitis, Ewing's sarcoma and lymphoma. Objectives: To show the plain radiographic findings of LCH, that allow the radiologist to suspect it. Methods and materials: The clinical and radiological presentations of the biopsy proven LCH cases of the National Bone Tumor File (RENATO) between the years 1961 and 1999 were analyzed retrospectively. Results: From a total of 59 patients, 58% were boys and 42% were girls. Age ranged from 0.8 to 17 years, with an average of 6.1 years. Medical history was obtained in 56 cases (95%). The mean duration of symptoms at diagnosis was 5,5 months, with pain at the site of affection being the most frequent 50/59 of them. Forty-eigth patients (81%) presented with a solitary bone lesion and 11 (19%) presented with two or more lesions; 35 patients had afection of long bones and 26 of axial skeleton. The most frequently radiological pattern was a purely osteolytic lesion (n=45). 13 patients presented with a permeative lesion and a vertebra plana was found in 3. Periostal reaction and soft tissue mass were found in 30 and 29 cases respectively. Conclusions: Despite the fact that LCH has several radiological manifestations, its diagnosis should be suspected by the radiologist. This study with biopsy proven cases of Langerhans´ cell histiocytosis allows us to characterize the manifestations of this disease in the skeleton and is useful for the differential diagnosis of a bone lesion in the pediatric patient.

Rev Chil Radiol 2005; 11(1):9-12. 9 RADIOLOGIA DIGESTIVA Llanos J, y cols. Invaginación colo-colica: Presentación de dos casos. Rev Chil Radiol 2005; 11: 9-12. Abstract: Intussusception is an uncommon event in adults, with different clinical presentations, which range from bowel obstruction symptoms to nonspecific abdominal pain. Can occur in the small or large bowel. In adults there is usually an underlying cause, usually benign or malignant neoplasms, being the latter the main cause of this disease in the colon. The diagnosis with CT is usually straightforward, with a very typical appearance. We report two cases of patients with bowel obstruction and diagnosis of intussusception caused by a lipoma and colon cancer respectively.

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