BACKGROUND:Resistance by disease causing organisms to antimicrobial drugs is a worldwide issue. Infections caused by resistant microorganisms fail to respond to conventional treatment, resulting in prolonged illness and hospitalization, and greater risk of death. Novel resistance mechanisms have emerged, making the most recent generation of antibiotics almost ineffective. OBJECTIVE: To study the antimicrobial sensitivity pattern in Kannur medical college hospital. MATERIALS AND METHODS: The present study is a retrospective hospital-record based study, conducted in Kannur medical college hospital from 1.08.2013 to 30.09.2013. During the period of study all the blood, urine, pus, and sputum culture reports were studied, from the register of central microbiology laboratory. Among the positive culture reports, antibiotic sensitivity of the common bacteria isolated were also noted to determine the antibiotic sensitivity pattern. RESULTS:The most common bacteria isolated in urine sample was enterobactericae sensitive to nitrofurantoin, amikacin and gentamycin; that in pus sample was Staph. aureus sensitive to linezolid and vancomycin; that in sputum sample was klebsiella sensitive to cefaperazone and sulbactum and that in blood sample was Staph. aureus sensitive to linezolid, vancomycin and gentamycin. CONCLUSION: The study gives one time information about the antibiotic sensitivity pattern, the intermittent review of the sensitivity pattern is very essential.

Nosocomial outbreaks related to medication contamination are reported world-wide. A sudden increase in cases of Achromobacter spp. bacteremia led to an outbreak investigation in our setting. Line listing and environmental sampling led to identification of contaminated furosemide ampoules as the source. Molecular identification helped in species identification and in SUMMARYthis outbreak more than one species was identified. Prompt withdrawal of the contaminated batch of ampoules curtailed the outbreak.