Background: Pregnancy leads to profound alterations in the respiratory system of the mother, leading to alteration in the normal course of common pulmonary diseases. However there is insufficient information regarding the changes in respiratory parameters of smaller airways in different trimesters of pregnancy. Objective: This study was designed to evaluate the pulmonary function tests in 1 st , 2 nd and 3 rd trimesters of pregnancy & compare them with non-pregnant control group. Methods: A cross-sectional study was carried in 200 healthy women in the age range of 19-35 years. The subjects were distributed in four groups, i.e control (non-pregnant) group and 1 st , 2 nd & 3 rd trimester pregnant groups. Number of subjects in each group was 50. We recorded respiratory parameters in control and study groups. Statistical analysis was done by 'Z' test. Results: There is significant decrease in FEV1, FEV1%, FEF25-75%, FEF25%, FEF50%, FEF75% in all trimesters of pregnancy with maximum decrease in 1 st trimester. Conclusion: The changes in pulmonary functions are attributed to the marked changes in the respiratory parameters during pregnancy. This knowledge of pulmonary function changes during pregnancy may be helpful in the prevention of gestational complications associated with an inadequate maternal respiratory adaptation.
Cardiopulmonary bypass is considered to be the common culprit for the occurrence of fever in the immediate post-operative period i.e, within 24 hours in pediatric patients. Other common causes contributing to fever are anaesthetic drugs, blood transfusions & pain. This early fever usually manifests as tachy-arrthymias in recovery room requiring interventions. This review intends to know the pathophysiology of fever and systemic inflammatory response syndrome after bypass (SIRAB) onset, preventive aspects and better management of the fever in the post-operative period.
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