OBJECTNonpowder guns, defined as spring- or gas-powered BB or pellet guns, can be dangerous weapons that are often marketed to children. In recent decades, advances in compressed-gas technology have led to a significant increase in the power and muzzle velocity of these weapons. The risk of intracranial injury in children due to nonpowder weapons is poorly documented.METHODSA retrospective review was conducted at 3 institutions studying children 16 years or younger who had intracranial injuries secondary to nonpowder guns.RESULTSThe authors reviewed 14 cases of intracranial injury in children from 3 institutions. Eleven (79%) of the 14 children were injured by BB guns, while 3 (21%) were injured by pellet guns. In 10 (71%) children, the injury was accidental. There was 1 recognized assault, but there were no suicide attempts; in the remaining 3 patients, the intention was indeterminate. There were no mortalities among the patients in this series. Ten (71%) of the children required operative intervention, and 6 (43%) were left with permanent neurological injuries, including epilepsy, cognitive deficits, hydrocephalus, diplopia, visual field cut, and blindness.CONCLUSIONSNonpowder guns are weapons with the ability to penetrate a child’s skull and brain. Awareness should be raised among parents, children, and policy makers as to the risk posed by these weapons.
Early feeding in preterm IUGR neonates with AREDF on antenatal UA Doppler allowed earlier discontinuation of PN, allowing birth weight to be regained earlier and did not increase the incidence of NEC and FI.
Asparagine synthetase deficiency is a rare inborn error of metabolism caused by a defect in ASNS, a gene encoding asparagine synthetase. It manifests with a severe neurological phenotype manifesting as severe developmental delay, congenital microcephaly, spasticity and refractory seizures. To date, nineteen patients from twelve unrelated families have been identified. Majority of the mutations are missense and nonsense mutations in homozygous or compound heterozygous state. We add another case from India which harbored a novel homozygous missense variation in exon 11 and compare the current case with previously reported cases.
The aim of this study was the introduction of a new linear ventricular measurement which has a better correlation with ventricular volume than the commonly used linear measurements, especially in chronically shunted patients with small and/or asymmetrical ventricles. Ventricular volume, brain volume, Evans ratio, Schierman index, cella media index and frontal and occipital horn ratio were measured from CT scans of 57 shunted hydrocephalic patients and 20 normal control children. Four groups of patients were identified with regards to the ventricular size and symmetry (small, large, symmetrical and asymmetrical). A new linear measurement was defined as half of the ratio of the frontal and occipital ventricular width to that of the skull (frontal and occipital horn width ratio; FOHWR) and compared to other linear measurements in different patient groups. FOHWR showed better correlation with ventricular size and ventricular brain ratio than the ventricular linear measurements currently in use, especially in chronically shunted patients with small and/or asymmetrical ventricles.
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