Epidemiological studies on odontogenic tumours conducted in different parts of the world emphasised variation in incidence and distributional pattern. Such epidemiological studies are obscured in Southern state of Andhra Pradesh in India. Present study was conducted at an institutional setup in South Indian population to assess the demographic data of odontogenic tumours. The retrospective study, which included all the odontogenic tumours from the archives of department of oral pathology, Dental teaching and Research Institution in southern part of India. Cases were selected based on the classification of WHO 2005 histopathological typing for odontogenic tumours and the assessment year considered was from 2002 to 2014. Demographic data was analysed for these tumours. Results were analysed using Chi-Square Test. Incidence of the odontogenic tumours was found to be 2.17%. Peak age incidence was recorded highest in third and fourth decade of life. Males were commonly involved [59%] with the male to female ratio of 1.43:1. Posterior mandible [53.4%] was the chief anatomical location involved with the tumours. Considering the individual lesions, Ameloblastoma [49%] was found to be more frequent, followed by Keratinizing cystic odontogenic tumour [32%], Odontome [6.2%], Adenomatoid odontogenic tumour [5.5%], Odontogenic myxoma [2.4%], Ameloblastic fibroma [0.6%], Calcifying epithelial odontogenic tumour [1.8%] and Squamous odontogenic tumour [1.2%]. The total frequency of odontogenic tumours was 2.17%. Ameloblastoma and Keratinizing cystic odontogenic tumours were the predominant tumours, demonstrating significant regional and geographic variation.

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Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete cellular subsets. The purpose of this short communication is to provide information regarding the heterogenecity of fibroblasts and its variability in physiological and pathological conditions.

Diagnostic laboratories must balance the utility of deeper levels with the additional time required and expense incurred and the impact on patient care. Deeper sections are inevitable in certain situations and periodical auditing of laboratory work will reduce the need for additional sections and delay in the dispatch of biopsy report.

Myofibroblasts (MFs) are modified fibroblasts that express features of smooth muscle differentiation and were first observed in granulation tissue during wound healing. These cells play a key role in physiologic and pathologic processes like wound healing and tumorigenesis. The presence of MFs has been reported in normal oral tissues and pathologic conditions like reactive lesions, benign tumors, locally aggressive tumors and malignancies affecting the oral cavity. This article briefly reviews the important hallmarks related to the discovery, characterization and tissue distribution of MFs in oral health and disease.