BACKGROUND Diabetes mellitus is a very common health problem in India. Pre-diabetes is defined by American Diabetes Association (ADA) as impaired fasting glucose (FBS 100-125 mg/dl), impaired glucose tolerance (plasma glucose 140-199 mg/dl after 75 gm 2 hrs. oral glucose tolerance test) or both. Lipid disorders are not atypical in diabetes. They contribute to the considerable increase in the risk of atherosclerosis and consequent mortality in diabetes and pre-diabetes. Hence, the present study aims at evaluating dyslipidaemia in pre-diabetic subjects. We wanted to study the prevalence of dyslipidaemia among prediabetic patients attending OPD in a tertiary care centre. METHODS An institution-based case control study was conducted over a period of 18 months in inpatient as well as the outpatient prediabetic patients at ESIC Hospital, Rajaji Nagar, Bangalore. Patients were screened for their glycaemic status by performing fasting sugar and post prandial glucose level or two hours oral glucose tolerance test. Qualifying patients underwent detailed history taking, clinical examination, fasting lipid profile and routine investigations. RESULTS After a thorough screening of a total of 100 patients with either Impaired Fasting Glucose (IFG) or Impaired Glucose Tolerance (IGT) or both, they were included in the case group and 100 patients with normal glucose levels were included as controls in the study after consideration of the inclusion and exclusion criteria. Dyslipidaemia was observed in 37 prediabetic patients and 16 patients in the control group. Out of the 100 patients with prediabetes (cases), the mean total cholesterol was 177.06 ± 27.16 mg/dl and the mean triglycerides were 145.25 ± 19.72 mg/dl, mean HDL-cholesterol was 46.88 ± 8.36 mg/dl, and mean LDL-cholesterol was 120.14 ± 15.85 mg/dl respectively. CONCLUSIONS Lipid disorders can be seen among prediabetes. Indians, being one of the groups with high prevalence of diabetes, diagnosis is often delayed through lifestyle interventions. Early identification and treatment of persons with prediabetic conditions has the potential to reduce both the incidence of diabetes as well as its complications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.