Fire accidents in high-rise buildings pose a serious threat to the lives and property of the occupants, and safe evacuation from a fire is difficult due to the dense population and the presence of various flammable materials. Therefore, the appropriate choice of the configuration form is likely to be the main factor in controlling the fire spread and its transmission speed to the upper floors and increasing the evacuation chance. The study adopted computer modeling and fire simulation technology from Pyrosim and FDS and presented the results by Smokeview. The simulation results showed that the risk of fire spreading in high-rise buildings increases as the increase of complicated of the form, and vice versa. Therefore, the study recommends the use of simple forms for high-rise buildings. The results of the research can be adopted and generalized to other buildings to reduce the impact of fires.