Background The selfie phenomenon is an emanating one, specifically affecting adolescents and young adults. It emerges as a reflection of a wide spectrum of neuropsychiatric disorders. Based on this, the current study aimed to assess the rate of the selfie phenomenon among Egyptian university students and its sociodemographic and psychiatric correlates. During the study procedure, we enrolled 200 undergraduate Egyptian university students from two different faculties and were assessed using the Selfie Behavioral Scale, Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Structured Clinical Interview for DSM-IV-TR Axis II Disorders, and Global Assessment of Functioning Scale. Results 49.5% of the students being assessed had borderline selfitis with a higher rate among females. We found a highly significant association between the selfie phenomenon and depression, anxiety, obsessive-compulsive disorder, eating disorders, and other psychiatric disorders and personality disorders, and we also found that selfies had a significant negative association with the level of functioning among students. Conclusions Results concur with previous existing literature regarding the magnitude of the selfie phenomenon and its relationship with different psychiatric disorders and personality disorders.