Reports of the incidence of the cyst of Montgomery, a rare condition of the breast, affecting mainly adolescent female, are scarce in the literature. This cyst develops from an obstruction of the small papular projections at the edge of the areola called Montgomery tubercles. It could be a simple asymptomatic mass or an inflamed symptomatic mass. We report two cases encountered this year. The first case was a 15-year-old female who complained of bilateral breast pain and a right breast mass. Laboratory tests were unremarkable. A diagnosis of noninflamed Montgomery cyst based on clinical and sonographic examination was made. An antibiotic was recommended. The second case was a 13-year-old female who complained of pain and swelling with redness in the right breast. Laboratory tests were unremarkable. Sonographic examination revealed a right retroareolar cyst containing turbid echogenicity with surrounded hyperemia. A diagnosis of inflamed Montgomery's cyst was made. Medical treatment was successful without any surgical intervention. Both patients had favorable outcomes at follow-up visits. This stresses the importance of a proper recognition of the pathology, incidence, diagnosis and management of the cyst of Montgomery in the pediatric age group.
BACKGROUND: Breast cancer is the most commonly diagnosed malignancy in women worldwide. Mammography is the best screening method for the early detection of breast cancer in asymptomatic women; however, its results are associated with high false positive/negative rates. One factor that decreases the sensitivity of mammography-based diagnosis of breast cancer is breast density. This study aimed to identify the association between mammographically determined breast density and breast cancer.METHODS: This single-center retrospective study included 2158 female participants in the Eastern Province of Saudi Arabia who underwent mammography between 2016 and 2018. We evaluated baseline information on breast density and its relationship with breast cancer risk and other factors (age, age at first childbirth, menopause status, and family breast cancer history). Mammogram reports were categorized using the Breast Imaging Reporting and Data System lexicon. RESULTS: The majority (39%) of participants showed scattered fibroglandular density and Breast Imaging Reporting and Data System category 2 (62.5%), while the occurrence of extremely dense breasts was low (4.7%). Breast density was found to be associated with age and menopause status (p < 0.0005). Participants with Breast Imaging Reporting and Data System assessment categories 4 (suspicious for malignancy) and 5 (highly suggestive of malignancy) were associated with elevated breast cancer risk (confirmed by biopsy).CONCLUSION: Breast density was not found to be associated with breast cancer risk in this study. However, the proportion of participants with extremely dense breasts was very low (4.7%). Therefore, further studies are warranted with larger sample sizes including extremely dense breasts.
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