Cefdinir, a third-generation oral cephalosporin frequently used in pediatric populations, may cause red stools when administered with iron or products that contain iron, such as infant formula. This benign side effect is not well documented in the medical literature. We describe a 7-month-old girl who was evaluated for red stools while taking cefdinir along with an oral iron supplement. Cefdinir is a commonly prescribed antibiotic in pediatric populations because of its once-daily dosing and its indications for acute otitis media, pharyngitis, acute sinusitis, and uncomplicated skin infections. Maroon-or red-colored stools are a known side-effect of cefdinir that have been infrequently reported in the medical literature. The manufacturer states that "there have been reports of reddish stools in patients receiving cefdinir," and adds that in many of these reports, patients were also receiving products containing iron.
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