Efeitos da morfina e da metadona associadas à acepromazina em gatas anestesiadas com propofol e halotano e submetidas à ovariossalpingohisterectomiaEffects of morphine and methadone associated with acepromazine in cats anesthetized with propofol and halothane and subjected to ovariossalpingohisterectomia RESUMO Os fármacos utilizados na medicação pré-anestésica são úteis para preparar o paciente para anestesia, causando sedação, analgesia, redução na dose dos anestésicos e menor incidência de efeitos adversos ao paciente. O objetivo deste trabalho foi avaliar os efeitos cardiovasculares e respiratórios, comportamentais, relaxamento muscular, analgesia pós-operatória da morfina ou metadona associadas à acepromazina em gatas anestesiadas com propofol e halotano e submetidas a ovariossalpingohisterectomia. Para isso, foram utilizadas 20 gatas clinicamente sadias, distribuídas em 2 grupos: o grupo I recebeu a associação de acepromazina (0,05mg/kg) e metadona (0,2mg/kg) e o grupo II recebeu a associação de acepromazina (0,05mg/kg) e morfina (0,2mg/kg) administradas na mesma seringa por via intramuscular. Foram avaliados frequência cardíaca e respiratória, pressão arterial sistólica, saturação de oxi-hemoglobina, concentração de dióxido de carbono no ar expirado, temperatura retal e tempo de preenchimento capilar, nos períodos pré, trans e pós-operatórios. Pode-se concluir que ambas as associações produziram leve sedação e podem ser utilizadas com segurança em felinos, pois promoveram boa analgesia sem efeitos colaterais. ABSTRACTThe pre-anesthetic medication is useful to prepare the patient for anesthesia, causing sedation, analgesia, reduction of the anesthetic gas doses and a lower incidence of adverse effects to the patient. Such variation of effects is dependent on the combination of drugs used. The aim of this study was to evaluate the cardiovascular and respiratory effects, behavioral, muscle relaxation, postoperative analgesia and influence on the quality and recovery period of morphine or methadone. For that were used 20 clinically healthy cats, divided into 2 groups: group I received the combination of acepromazine (0.05mg/kg) and methadone (0.2mg/kg) and group II received a combination of acepromazine (0.05mg/kg) and morphine (0.2mg/kg) administered in the same syringe for intramuscular injection. It was concluded that both associations produced mild sedation and can be used safely in cats, therefore providing good analgesia and muscle relaxation, without side effects.
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