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This paper reports the objective intervention of the Hospital Dentistry team of the Beneficent Association of Campo Grande Santa Casa, contemplating a multi-professional approach to present Low-Level Laser Therapy (LLLT) as a therapeutic alternative for the treatment of individuals with Stevens-Johnson Syndrome (SJS). Male patient, 13 years old, with an initial complaint of pain, edema and burning mouth was treated by in situ applications of LLLT - Aluminium Gallium Indium Phosphide - InGaAlP type diode Laser (Laser duo / DMC Therapy XT, São Carlos, SP, Brazil), to promote photobiomodulation and subsequent repair of the compromised mucosa. Monitoring the patient during four laser therapy sessions with 24-hour intervals between them revealed a favorable evolution of the clinical picture with tissue repair, decreased pain and consequent oropharyngeal homeostasis. The favorable results consolidate LLLT as an alternative to be adopted with considerable effectiveness in combating pain and tissue changes in the oral mucosa resulting from the SJS.

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Paracoccidioidomycosis (PCM) is a deep fungal infection, endemic with considerable morbidity in South America, whose first symptoms can occur in the oral cavity. A 47-year-old male patient, leucoderma, living on the streets, presenting dyspnea, pain during the speech, and dysphagia, was referred for admission to the ICU for suspected COVID-19 infection. The intensive care physician's evaluation revealed a tongue lesion with suspected carcinoma. By dentist investigation, was observed the presence of moriform lesions with high borders delimitation in the tongue. Also, granulomatous ulcers with irregular texture, suggesting moriform stomatitis, the chest tomography revealed diffuse thickening of the bronchial walls, indicating chronic bronchopathy with discrete centrilobular nodules, sometimes confluent. Incisional tongue biopsy associated with lung imaging confirmed the diagnosis of PCM, and the patient was referred to the referral center for the treatment of fungal diseases. The involvement of the oral environment as a region to the appearance of detectable first symptoms of PCM suggests the need for the oral evaluation by a specialist as a diagnostic tool.