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Objectives: There are controversies about the role of zinc in the development of both types 1 and 2 diabetes. The aim of this study was to assess serum zinc level in diabetic patients with and without peripheral neuropathy in comparison to healthy controls and to explore the possible relationship between serum zinc level and severity of peripheral neuropathy. Methods: This case control study was conducted on 120 subjects: 40 patients fulfilled the criteria for diagnosis of probable diabetic polyneuropathy (DPN), 40 diabetic patients without polyneuropathy (N-DPN) and 40 healthy controls. DPN patients were submitted to clinical assessment of diabetic neuropathy using neuropathy symptom and change (NSC) scale, Michigan Neuropathy Screening Instrument Physical Assessment (MNSI) scale and electrophysiological assessment using nerve conduction study.Zinc serum level was measured in all subjects included in this study using direct colorimetric test method.Results: Diabetic patients with and without neuropathy were found to have significantly lower mean values of serum zinc than healthy controls (p = .025, .03 respectively). There is a statistically significant negative correlation between zinc serum level and hemoglobin A1C (HA1C) (p ˂ .001), NSC score (p = .001) and MNSI score (p = .003) in DPN group. There were also statistically significant correlations between zinc serum level and nerve conduction study values. Conclusion:Zinc deficiency significantly correlates with the severity of DPN and glycemic control.

The aim of current study was to detect prevalence and clinical presentation of iron deficiency anemia (IDA) in primary school children in Beni-Suef and to assess their risk factors. This crosssectional survey was conducted on randomly selected primary school children with microcytic hypochromic anemia of both genders aged from 6 years -12 years in Beni-suef governorate.The prevalence of IDA was 26.6% among children 6-12 years of age. Socioeconomic factors (such as mother education, residence, nutritional status, parasitic infection and recurrent infection) and poor dietary habits are the main contributing factors of IDA among the children studied. It is alarming that the prevalence of IDA is high among children 6-12years of age.Screening for IDA should be directed at high-risk groups and school programs should be implemented to improve awareness of healthy food habits.

Background: Diabetes mellitus continues to be an important clinical problem throughout the world In 2014, 8.5% of adults aged 18 years and older had diabetes. In 2015, diabetes was the direct cause of 1.6 million deaths. Objectives: To investigate the role of retinol binding protein (RBP) in the early stage of diabetic nephropathy, in patients with type 2 diabetes mellitus (T2DM). Methods: This cross-sectional observational study recruited patients with longstanding T2DM and healthy control subjects. Patients with T2DM were further stratified based on their urine albumin-creatinine ratio (UACR). Urinary concentrations of RBP were determined using an enzyme-linked immunosorbent assay.

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