This study aims to contribute to the development of message design. This designing is aimed to enhance student memory and support their knowledge recall. Therefore, the study assesses the impact of colors (Red-Green-Purple-Cyan) and their effect when used in designing educational infographic message for students with relation to their retrieve functionality. To achieve the goal of the study, the researchers follow the quasi-experiment methodology, using five tools which vary in terms of words, sentences, and images. A total of 87 female students at King Saud University from different fields (Islamic Studies, Quranic Studies, Art Education, Special Needs Education, Psychology and Computer Science). The study found that there is a significant relationship (0.05 ≥ α) between the colors usages in designing educational infographic message and level of students' recall for students. It also found the significant level at (0. 05 ≥ α) impact of colors, particularly for red, on recall's level of the students when used in designing educational infographic message. Also, the researchers recommend studying different colors in divergent fields to present an educational message such as educational media, educational software, educational websites, images, books, social networking etc. which can enhance the learning competence of the students.