Background: Although it is generally accepted that the haemoglobin concentration decreases and white cell count increases during normal pregnancy, there is less accord regarding changes in platelet indices. Present study was performed to know the relation of platelet indices with normal pregnancy, preeclampsia and severity of pre-eclampsia.Methods: Hundred pregnant women were studied at Department of Obstetrics and Gynaecology, PCMS and RC, Bhopal after dividing them in two Group N (n=50, normal pregnant women) and Group P (n = 50, pre-eclampsia patient). Platelet indices including platelet count mean platelet volume and platelet distribution width were estimated in all the patients. Data were analyzed using IBM SPSS ver. 20 software. Level of significance was assessed at 5%.Results: In Group P [34 (68%)] and Group N [21 (42%)] most of the patients had platelet count of <2 lac respectively. Whereas Group P, 16 (32%) patients had thrombocytopenia (platelet count between 50-1.5 lac) where as in Group N, none of the patients had lower platelet count. Most of the patients (55%) in study cohort had PDW of 15 fl out of that half of the patients in Group N had PWD as 15 fl whereas in Group P 60% had PDW value as 15 fl. Out of 50 preeclampsia patients 24 (48%) were of severe type, out of which 54% had platelet count <1.5 lac, 83% had PDW as 15-16fl, and 54% had MPV in the range of 10-11 fl.Conclusions: Platelet count decreases while MPV and PDW increase as pregnancy advances, and these changes are more pronounced in preeclampsia than normotensive pregnancy.

Background: Postoperative wound gaping is a very traumatic event both for patient and treating doctor as it adds economical and psychological burden to the patient and the family. This study was conducted with the aim to find out the various factors affecting postoperative wound gaping and their outcome in obstetrical and gynecological abdominal surgeries.Methods: This Retrospective observational study was carried out in the Department of Obstetrics and Gynecology at Peoples College of medical sciences and research Centre, Bhopal, India from 1st May 2014 to 31st October 2015.Results: A total of 1310 patients underwent major obstetrical and gynecological abdominal surgeries, out of which 29 cases developed postoperative wound gaping with the percentage being 2.2%. The rate was found to be higher among the emergency obstetric case (51.7%). Associated risk factors being anemia (72%), obesity (65%), hypoproteinemia (62%) and diabetes (52%) among gynecological surgeries and prolonged rupture of membranes (53%), emergency LSCS and previous LSCS (47%) among the obstetric cases. The common causative organism was found to be E. coli (28.5%) followed by acinetobacter and pseudomonas.Conclusions: Anemia, obesity, hypoproteinemia, diabetes, history of previous surgeries, emergency operations are the high risk factors for wound gaping in both obstetrics and gynecology surgeries. Correction of anemia, diabetes preoperatively, high protein diet and prevention of other risk factors like avoiding prolonged labor, use potent antibiotics in cases of rupture of membrane, timely intervention, provide well equipped wards with clean environment would be rewarding for better outcome of the surgery.

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Background: To analyze the cases of Obstetric Hysterectomy in view to evaluate the incidence, indication, maternal risk factors and complications associated with the surgery. Methods: Retrospective Observational analytical study of cases of obstetric hysterectomy performed at Obstetrics and Gynecology department of People's Medical College and Research Centre, Bhanpur, Bhopal over a period of seven years was done. Evaluation of Maternal age, parity, gestational age, indication for hysterectomy, the type of operation performed, blood loss, blood transfused, complications, and hospitalization period was done. Results: The overall incidence of Obstetric hysterectomy in our study was found to be 0.33%, with a maximum number of patients 7 (33%) in the age group of 26-30 yrs. Patients who were para 3 or more were-12 (63%). The causes for an obstetric hysterectomy were PPH-12 (63%); placenta previa-5 (26%); ruptured uterus-4 (21%). 9(47%) patients had a history of previous caesarean section. Out of the 19 hysterectomies performed, 12(63%) were total hysterectomy and 7(37%) were subtotal hysterectomy. Fever was the commonest complication 7(37%). There were two maternal deaths. Conclusions: Obstetric hysterectomy is a lifesaving procedure. The outcome depends on timely decision, good clinical judgement and professional surgical technique. It reduces maternal morbidity and mortality.

This study aims at determining the normogramme of birth weight for preterm, full term, post term births and also for SGA, AGA, LGA domain. The objective is to identify the group of infants who need intensive neonatal care. METHODS: Retrospective analytic study was conducted on 2,627 new born which are screened by birth weight and their gestational age Other variables like sex & NICU admission for different AGA, SGA, LGA domain were also analyzed. RESULTS: Study includes 68 % full term, 28% preterm and 4% post mature newborn. Infant category AGA were 57%, SGA 40% and LGA 2%. SGA domain infant maximum was 54% and 59%in full term &post term respectively. However for preterm infants AGA domain was maximum of 61%.NICU admission of LGA and SGA domain was 30-31 % and only 25% for AGA infants which was significant. CONCLUSION: 44% of preterm infants, 30% of SGA & LGA need critical observation at birth.