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Squeeze-and-excitation (SE) module enhances the representational power of convolution layers by adaptively re-calibrating channel-wise feature responses. However, the limitation of SE in terms of attention characterization lies in the loss of spatial information cues, making it less well suited for perception tasks with very high spatial inter-dependencies such as semantic segmentation. In this paper, we propose a novel squeeze-and-attention network (SANet) architecture that leverages a simple but effective squeeze-and-attention (SA) module to account for two distinctive characteristics of segmentation: i) pixel-group attention, and ii) pixel-wise prediction. Specifically, the proposed SA modules impose pixel-group attention on conventional convolution by introducing an 'attention' convolutional channel, thus taking into account spatial-channel inter-dependencies in an efficient manner. The final segmentation results are produced by merging outputs from four hierarchical stages of a SANet to integrate multi-scale contexts for obtaining enhanced pixel-wise prediction. Empirical experiments using two challenging public datasets validate the effectiveness of the proposed SANets, which achieved 83.2% mIoU (without COCO pre-training) on PASCAL VOC and a state-of-the-art mIoU of 54.4% on PASCAL Context.

While microscopic analysis of histopathological slides is generally considered as the gold standard method for performing cancer diagnosis and grading, the current method for analysis is extremely time consuming and labour intensive as it requires pathologists to visually inspect tissue samples in a detailed fashion for the presence of cancer. As such, there has been significant recent interest in computer aided diagnosis systems for analysing histopathological slides for cancer grading to aid pathologists to perform cancer diagnosis and grading in a more efficient, accurate, and consistent manner. In this work, we investigate and explore a deep triple-stream residual network (TriResNet) architecture for the purpose of tile-level histopathology grading, which is the critical first step to computer-aided whole-slide histopathology grading. In particular, the design mentality behind the proposed TriResNet network architecture is to facilitate for the learning of a more diverse set of quantitative features to better characterize the complex tissue characteristics found in histopathology samples. Experimental results on two widely-used computer-aided histopathology benchmark datasets (CAMELYON16 dataset and Invasive Ductal Carcinoma (IDC) dataset) demonstrated that the proposed TriResNet network architecture was able to achieve noticeably improved accuracies when compared with two other state-of-the-art deep convolutional neural network architectures. Based on these promising results, the hope is that the proposed TriResNet network architecture could become a useful tool to aiding pathologists increase the consistency, speed, and accuracy of the histopathology grading process.

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